Big Picture – A Deep Dive Examination of IXICO PLC
IXICO PLC Snapshot
As a trusted partner to the global biopharma industry, our technology enabled specialty services are used to, select patients for clinical trials, assess the safety and efficacy of new drugs in development and in post marketing surveillance.
Our strong scientific heritage and deep understanding of neurological diseases enable us to collaborate with clinical, academic and pharmaceutical partners to develop and deploy new digital technologies targeted at improving the assessment of patient outcomes.
We are neuroscience experts in image data management and analysis.
Our greatest assets are our talented people developing and deploying innovative digital technologies.
Quality drives our operational excellence. We support our people to be the best they can be through continuous learning and development.
We conduct our business to the highest ethical standards and strive to be a trusted partner of choice.
Since 2004 our technology, scientific expertise and clinical data management and analysis capabilities have been selected to support clinical trials for the majority of the top pharmaceutical and speciality biotechnology companies.
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Neurological disease focus
Alzheimer’s Disease (AD)
AD is a chronic neurodegenerative disease and is represented in 60-70% of cases of dementia. In 2015, there were approximately 29.8 million people worldwide living with AD. It affects around 6% of people aged 65+ years. There are currently no treatments to halt or reverse its progression. There is significant ongoing research to better understand and treat AD. We have supported important AD research since 2007 and continue to assist many pharmaceutical companies in their search for novel therapies.
Parkinson’s Disease (PD)
PD is the second most common neurodegenerative disease, after Alzheimer’s disease. An estimated 7 to 10 million people worldwide are living with PD. The combined direct and indirect cost of PD, including treatment, social security payments and lost income from inability to work, is estimated to be nearly $25 billion per year in the United States alone. There has been significant research over the past 50 years, resulting in important discoveries and treatments which provide relief. We first supported a clinical study for PD in 2016.
Huntington’s Disease (HD)
HD is a rare genetic neurodegenerative disorder that affects the patient’s normal movement, cognition and behaviour. HD is more common in people of Western European descent than in those of Asian or African ancestry, affecting approximately 5-7 people per 100,000 in Western countries. There are currently no effective marketed treatments for HD. Interest in developing therapeutics to treat the disease within the pharmaceutical industry is significant with a large number of pharmaceutical and biotechnology companies working in this indication. We have supported important research in HD since 2007.
Progressive Supranuclear Palsy (PSP)
PSP is a Parkinson’s-like neurological condition caused by the premature loss of nerve cells in certain parts of the brain, which leads to difficulties with balance, movement, vision, speech and swallowing. Research suggests around 20,000 people suffer with PSP in the United States alone. There are currently no effective marketed treatments for PSP. There is growing momentum in PSP research and we have supported clinical trials in this area since 2015.
Cerebrovascular diseases are conditions caused by problems that affect the blood supply to the brain and can result in vascular dementia. Cerebrovascular disease primarily occurs with advanced age and the risk increasing after 65 years of age. We have supported cerebrovascular disease research since 2012.
Multiple Sclerosis (MS)
MS is a condition that affects the brain and spinal cord. It is the most common autoimmune disorder affecting the central nervous system, affecting around 2.3 million people globally as of 2015. Ongoing research is focused on developing more effective disease-modifying and symptomatic treatments as well as the creation of therapies for the progressive types of MS. We have been involved in MS since 2015 through our AssessaPML collaboration with Biogen.
Unique imaging and data management with science – at scale
We have the capability, scale and experience to provide clinical trial services across all trial phases.
Our platform has been developed by our experts as a scalable and secure infrastructure for the standardisation, capture, analysis and reporting of regulatory compliant clinical data. This enables you to make rapid, better informed, clinically meaningful decisions.
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How we work
Global, multi-site standardisation
Working with our network of qualified clinical sites worldwide, we deliver innovative, regulatory compliant technology solutions. By providing compliant data standardisation, collection and analysis we support our biopharma clients’ regulatory submission, establishing IXICO as a trusted partner.
Our deep understanding of neuroimaging underpins everything we do. Our multi-disciplinary team support you from project design through to close with our unique end-to-end data management and image analysis platform.
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15 Long Lane
IXICO Technologies Inc.
225 Cedar Hill Street
Marlborough, MA 01752
IXICO plc is incorporated and registered in England and Wales with registered number 03131723. The Group operates from its headquarters in London, UK.
4th Floor, Griffin Court, 15 Long Lane, London EC1A 9PN
Nominated Advisor and Broker
Shore Capital and Corporate Limited
Bond Street House, 14 Clifford Street, London, W1S 4JU
Shore Capital Stockbrokers Limited
Bond Street House, 14 Clifford Street, London W1S 4JU
T +44 (0)20 7408 4080
Equiniti Registrars Limited
Aspect House, Spencer Road, Lancing, West Sussex, BN99 6DA
T +44 (0)871 384 2030
Chartered accountants and statutory auditors
Grant Thornton UK LLP
101 Cambridge Science Park, Milton Road, Cambridge CB4 0FY
T +44 (0)1223 225600
100 Victoria Embankment, London, EC4Y 0PH
T +44 (0)20 7400 8000
Financial public relations
FTI Consulting LLP
200 Aldersgate, Aldersgate Street, London, EC1A 4HD
T +44 (0)20 3727 1000