Tiziana Life Sciences Ltd (NASDAQ:TLSA) CEO Ivor Elrifi talked with Proactive about the company’s latest milestone: dosing the first patient in its Phase 2a clinical trial targeting multiple system atrophy (MSA), a rare and fatal neurodegenerative condition with no approved treatment.
Elrifi explained the trial involves the company's investigational monoclonal antibody, Foralumab, which is administered intranasally and aims to reduce neuroinflammation. “We’re trying to convert activated microglia into suppressed microglia,” he said, noting that these immune cells are linked to brain inflammation seen in several diseases, including MSA.
Baselode Energy Corp (TSX-V:FIND, OTCQB:BSENF) said on Friday it had closed a C$6 million private placement, with proceeds earmarked for uranium exploration in Canada’s Thelon and Athabasca Basins.
The offering, led by Red Cloud Securities Inc., included the full exercise of the agent’s option and saw the company sell 42.86 million flow-through units to charitable purchasers at C$0.14 each.
Nextech3D.AI (CSE:NTAR, OTCQX:NEXCF) said on Friday it is developing a blockchain-based software-as-a-service (SaaS) ticketing platform aimed at the global event industry, including concerts, conferences, trade shows and festivals.
The platform’s core feature, the “Event-Token,” will serve as both a secure, verifiable ticket and a tradable digital collectible, enabling fraud prevention, secondary market sales, and post-event engagement, the company said.
NEXE Innovations Inc (TSX-V:NEXE, OTC:NEXNF) said on Friday it has made another delivery to ecoBeans Coffee Inc., following strong early sales on Amazon Canada.
Following the launch of its products on Amazon in April 2025, ecoBeans reported that revenues for the two months following the launch were more than four times higher than during the initial period, driven by organic customer adoption across Canada.
Ocean Power Technologies Inc (NYSE-A:OPTT) has called on New Jersey lawmakers to strengthen support for the state’s emerging marine energy industry, citing its potential to create jobs, bolster climate resilience and enhance national security.
Speaking at a joint hearing of the New Jersey Assembly Environment, Natural Resources, and Solid Waste Committee and the Senate Environment and Energy Committee, OPT CEO Philipp Stratmann said the state’s coastline, workforce and industrial base position it to lead the US in tidal and wave energy.
HIVE Digital Technologies (TSX-V:HIVE, NASDAQ:HIVE) reported record quarterly revenue, net income and adjusted EBITDA on Friday, boosted by a sharp rise in Bitcoin mining hashrate and strong demand for its high-performance computing (HPC) hosting services.
Revenue for the fiscal first quarter ended June 30 jumped to $45.6 million, up from the prior quarter, as average mining capacity rose 45% sequentially to 8.7 exahashes per second (EH/s) and Bitcoin prices edged higher.
Digi Power X Inc (NASDAQ:DGXX, TSX-V:DGX) saw its colocation revenue jump 163% year-over-year in the first half of 2025 to $9.57 million, driven by rising demand for AI infrastructure.
The Miami-based company also removed a “going concern” risk during the quarter, a move that it said strengthened its balance sheet.
G Mining Ventures Corp (TSX:GMIN, OTCQX:GMINF) said it expects a stronger second half of 2025 as its flagship Tocantinzinho (TZ) mine in Brazil enters steady-state operations, following a quarter of record free cash flow, revenue, and plant throughput.
Second-quarter gold production climbed 20% from the prior quarter to 42,587 ounces, representing about 23% of the midpoint of full-year guidance.
How do you make the leap from biomass to Bitcoin and battery storage?
Active Energy Group PLC (AIM:AEG, OTCQB:ATGVF). The pivot, or should I say full 180, has been something of a life-saver, in commercial and corporate terms at least.
Asiamet Resources Ltd (AIM:ARS, OTC:KMGLF) has commenced limestone resource drilling at the Rinjen prospect, located about 12 kilometres north of its BKM copper project in Central Kalimantan, Indonesia.
The initiative aims to source local limestone for the project’s processing plant, reducing reliance on more expensive imported lime.
Hemogenyx Pharmaceuticals PLC (LSE:HEMO, OTC:HOPHF) has completed the first adult dose cohort in its ongoing Phase I clinical trial for HG-CT-1, a CAR-T therapy for relapsed or refractory acute myeloid leukemia.
"Completing the first adult dose cohort is a major achievement in our Phase I trial of HG-CT-1," said Hemogenyx chief executive Dr. Vladislav Sandler.
Union Jack Oil PLC (AIM:UJO, OTCQB:UJOGF) told investors it has spudded the Sark well in Central Oklahoma, USA.
“The high-impact Sark well is of major importance to Union Jack, both financially and operationally,” said executive chair David Bramhill.
Fortuna Metals Limited (ASX: FUN), formerly Lanthanein Resources Ltd (ASX:LNR, OTC:FRNRF), has confirmed its name change following shareholder approval on August 1, 2025. The change has been registered with the Australian Securities and Investments Commission (ASIC).
From the market open on Wednesday, August 20, 2025, the company will commence trading under its new name and ASX ticker code ‘FUN’, replacing the previous code ‘LNR’.
Provaris Energy Ltd (ASX:PV1, OTC:GBBLF) earlier this week outlined progress on the front-end engineering design (FEED) program for its proprietary large-scale low-pressure liquid carbon dioxide (LCO₂) tank.
American Rare Earths Ltd (ASX:ARR, OTCQB:ARRNF) has reported the first production of high-purity light and heavy rare earth oxide (LREO and HREO) concentrates from its Halleck Creek project in Wyoming, with purities of 96.4% and 97.1%, respectively. Both are critical feedstocks for permanent magnets, widely used in defence, clean energy and advanced technology applications.
Lindian Resources Ltd (ASX:LIN, OTC:LINIF) earlier this week announced it had secured formal approval from the Government of Malawi to extend the mining license area for the Kangankunde Rare Earths Project from 900 hectares to 2,500 hectares. Executive chairman Robert Martin sat down with Proactive to discuss the milestone.
Recce Pharmaceuticals Ltd earlier this week reported strong preclinical data for its RECCE® 327 Topical Gel (R327G). Chief executive James Graham told Proactive the gel was effective against two antibiotic-resistant bacteria and also accelerated wound healing.
Buru Energy Ltd (ASX:BRU, OTC:BRNGF) earlier this week outlined details of a new deep gas target named Flying Fox, located beneath its proven Rafael gas and condensate field in Western Australia’s onshore Canning Basin. CEO Thomas Nador talked with Proactive about this latest milestone.
