Percheron Therapeutics Ltd (ASX:PER, OTC:PERCF) has welcomed new preclinical data published in Cell Reports, demonstrating that its investigational antibody HMBD-002 enhances the effects of radiotherapy in squamous cell carcinoma of the head and neck (SCCHN).
Conducted by a team at Stanford University under the leadership of Professor Quynh-Thu Le, the study showed that combining HMBD-002 with radiotherapy significantly prolonged survival in mouse models. These findings underscore the potential of targeting VISTA, HMBD-002’s molecular target, to overcome resistance mechanisms and improve treatment outcomes.
Black Swan Graphene (TSX-V:SWAN) told investors that it has ordered a new production unit that will more than triple its annual graphene production capacity to 140 tonnes as part of its ongoing effort to scale up the supply of graphene-enhanced masterbatch (GEM) materials amid growing commercial engagement.
The new production unit will be installed at the company’s existing facility located at Thomas Swan & Co in the UK, Black Swan said in a commercial update on Tuesday.
Q2 Metals Corp (TSX-V:QTWO, OTCQB:QUEXF) is preparing its first exploration target for the Cisco lithium project in Quebec.
The Vancouver, BC-based company is estimating there could be between 215 and 329 million tonnes of rock containing 1% to 1.38% lithium oxide (Li₂O) at the target.
374Water Inc (NASDAQ:SCWO) has delivered and mobilized its AirSCWO 6 System to Clean Earth’s facility in Detroit to begin a series of commercial-scale demonstrations as part of a US Department of Defense (DoD) initiative to destroy PFAS-contaminated waste.
The testing campaign, expected to start in August following a three-week installation and commissioning period, is part of a previously announced project led by the Defense Innovation Unit (DIU) and the Environmental Security Technology Certification Program (ESTCP).
Scancell Holdings PLC (AIM:SCLP, OTC:SCNLF) has reported impressive interim data from its SCOPE cancer vaccine trial, prompting Panmure Liberum to upgrade its price target to 32p from 24p.
The biotech company, which specialises in therapeutic cancer vaccines, reported significantly improved response rates from the SCOPE trial involving 47 patients across three cohorts, substantially outperforming current standard treatments.
Gunnison Copper Corp (TSX:GCU, OTCQB:GCUMF) has begun mineral processing at its fully permitted Johnson Camp Mine (JCM) in southeast Arizona, with first copper sales expected in September.
The milestone comes about a year after construction of the site’s leach pad began, the company said.
Giyani Metals Corp (TSX-V:EMM, OTC:CATPF) announced a private placement which will raise up to C$3 million to advance its flagship K.Hill manganese project in Botswana.
The company said the proceeds will be used to fund ongoing workstreams and general working capital.
Reconnaissance Energy Africa Ltd (TSX-V:RECO, OTCQX:RECAF) announced it will spud its Kavango West 1X exploration well in Namibia before the end of July, targeting over 1,500 metres of Otavi carbonate reservoir in the Damara Fold Belt.
The well is expected to reach a total depth of approximately 3,800 metres, or 12,500 feet.
Midnight Sun Mining Corp (TSX-V:MMA, OTCQB:MDNGF) has kicked off an expansion drilling program at its Kazhiba-Main oxide copper target, part of the Solwezi Project in Zambia, as the company aims to define a maiden resource estimate later this year.
The new campaign follows a successful reverse circulation (RC) drill program in late 2024 that confirmed the presence of high-grade, near-surface copper mineralization, with standout intercepts including 10.7% copper over 21 metres and 5.6% copper over 26 metres.
Pantheon Resources PLC (AIM:PANR, OTCQX:PTHRF) has started drilling a new well, Dubhe-1, near the Ahpun oil field on Alaska’s North Slope.
The company, known for developing nearby Kodiak and Ahpun fields, aims to better understand the size and quality of oil and gas reserves close to existing pipelines and roads.
Scancell Holdings PLC (AIM:SCLP, OTC:SCNLF) has reported what it described as 'strong' phase II results for its experimental immunotherapy, iSCIB1+, showing a marked improvement in outcomes for patients with late-stage melanoma when added to standard treatments.
The UK-based life sciences group announced that its SCOPE trial, which is assessing the Immunobody DNA-based therapy in combination with established checkpoint inhibitors, showed an overall response rate of 69% in patients with a specific genetic marker.
IXICO PLC (LSE:IXI, OTC:PHYOF), the London-based brain imaging company, has expanded its partnership with the Global Alzheimer’s Platform Foundation (GAP) in a deal that gives it access to one of the world’s largest Alzheimer’s biomarker datasets.
The company said on Tuesday it had secured full data usage rights for GAP’s Bio-Hermes-002 study, an influential research programme aimed at speeding up the use of new Alzheimer’s biomarkers in clinical trials.
88 Energy Ltd (AIM:88E, ASX:88E, OTC:EEENF) reported steady progress across its global oil and gas portfolio in the quarter to 30 June.
At Project Leonis in Alaska, the company expanded its resource base with new lease awards and updated seismic data, now estimating a combined net mean prospective resource of 664 million barrels of oil across the Canning and Upper Schrader Bluff prospects.
Thor Explorations Ltd (TSX-V:THX, AIM:THX, OTC:THXPF) has released encouraging initial results from its first drilling campaign at the Guitry gold project in Côte d'Ivoire, confirming both near-surface and deeper gold mineralisation across multiple targets.
The company, which holds a 100% interest in Guitry, completed a 3,000 metre reverse circulation drilling programme in May and June.
Prescient Therapeutics Ltd (ASX:PTX, OTC:PSTTF) has extended the closing date of its Share Purchase Plan (SPP) to 5.00 pm (AEST) on Friday, July 25, 2025, following requests from shareholders for more time to participate. The extension provides additional time for eligible shareholders to apply for up to A$30,000 of new shares priced at A$0.040 each — a 16.7% discount to the 15-day volume weighted average price (VWAP) prior to the SPP announcement.
As a strong sign of support and confidence, all eligible directors have taken part in the SPP to date. The SPP is available to shareholders on record as of 7.00 pm (AEST) Monday, June 30, 2025.
More visible gold and copper mineralisation has been intersected at Solis Minerals Ltd (ASX:SLM, TSX-V:SLMN, OTCQB:SLMFF)'s 100%-owned Chancho al Palo Project in Peru, with a second diamond drill hole (CAP-002-2025) completed to a depth of 697 metres.