Destiny Pharma agrees research pact with Cystic Fibrosis Foundation
The company will assess the potential use of its XF-73 drug in treating people with cystic fibrosis that have contracted methicillin-resistant MRSA
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Destiny Pharma PLC is an innovative, clinical-stage biotechnology company focused on the development and commercialisation of novel medicines that can prevent life-threatening infections. The company's drug development pipeline includes two late stage assets NTCD-M3, a microbiome-based biotherapeutic for the prevention of C. difficile infection (CDI) recurrence which is the leading cause of hospital acquired infection in the US, and XF-73 nasal gel, a proprietary drug targeting the prevention of post-surgical staphylococcal hospital infections including MRSA.
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The company will assess the potential use of its XF-73 drug in treating people with cystic fibrosis that have contracted methicillin-resistant MRSA
XF-73 improved the performance against MRSA and Pseudomonas aeruginosa
The research on the medication, called XF-73, will be conducted in the US by Professor Stephen Sonis
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12 May 2022*A corporate client of Hybridan LLPDish of the dayJoiners:No Joiners Today.Leavers:No Leavers Today.What’s cooking in the IPO kitchen?Trade journal, the drinks business, reports that two drinks companies of vastly different sizes
Recently, Martina was senior vice president and deputy chief medical officer at Grunenthal Group
"Phase 3 trial design is due to be finalised in H1 2022, which should catalyse partnering discussions.“
The update was provided alongside the company's full-year results
The biotech firm said 12.9mln new shares are set to trade on AIM
Destiny Pharma is currently in advanced discussions with commercial partners for both assets
The board conceded that the timing of the share issue could have been better given the volatility of current markets but felt it better to bite the bullet rather than wait for a stronger market
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Essentially, researchers developing the nasal gel for postoperative infection will have to hit the same end-goal as they did in phase II
"We are very pleased with the encouraging data from our novel XF-73 dermal formulation which is aimed at meeting a clear clinical need in a large market where peak product sales could reach half a billion US dollars," said Destiny Pharma CE
NTCD-M3, which researchers are readying to phase III clinical trials, was the subject to a separate preclinical study by the US Department of Veterans Affairs
More than one million deaths occurred in one year due to bacterial Antimicrobial Resistance (AMR), whcih the company seeks to address with in-trial candidates.
Preclinical work on SPOR-COV, designed to prevent coronavirus infections, is progressing as planned
The study explored the link between Staphylococcus aureus decolonisation and Intensive Care Units infection rates
Destiny will have cross-reference rights to the data and so could start a similar skin infection clinical programme in the future
The company is blazing a trail in the infection arena and reckons it has two potential blockbuster treatments on its hands
"We are very pleased to announce this additional, positive data from the successful Phase 2b study of XF-73 as a novel drug to reduce the incidence of post-surgical infections such as MRSA."