Patient screening is well underway for Tryptamine Therapeutics Ltd (ASX:TYP, OTC:TYPTF)'s pioneering clinical trial investigating intravenous psilocin (TRP-8803) as a treatment for Binge Eating Disorder (BED), conducted in partnership with Swinburne University.
Swinburne has received a formal permit from the Victorian Department of Health to obtain and use controlled substances for research purposes. This regulatory milestone allows Tryp to start the supply of TRP-8803 to the university, with batch deliveries expected imminently and initial patient dosing scheduled for this quarter.
AMC Entertainment Holdings (NYSE:AMC) will report its second quarter earnings next week, with Wedbush analysts expecting a solid report with potential for upside.
“We remain positive into the Q2 print, which should highlight AMC’s strengths geographically and with its premium screens, likely driving market share gains,” analysts wrote.
Midnight Sun Mining Corp (TSX-V:MMA, OTCQB:MDNGF) announced that it has begun diamond drilling at its flagship Dumbwa target on the Solwezi project in Zambia.
The company said that drill locations were determined following a review of geochemical sampling, airborne VTEM survey data, previous drill results, and a recent dipole-dipole induced polarization (IP) survey.
Excellon Resources Inc (TSX:EXN, OTCQB:EXNRF) said on Wednesday that rehabilitation work is underway at its fully permitted Mallay Mine in Peru, with the goal of restarting production and reaching nameplate capacity of 600 tonnes per day by the second quarter of 2026.
In a letter to shareholders, CEO Shawn Howarth called the past few months a “transformative new chapter” for the company, noting that the acquisition of Mallay positions Excellon to become an emerging global silver producer.
Century Lithium Corp. (TSX-V:LCE, OTCQX:CYDVF) announced that its Angel Island lithium project in Esmeralda County, Nevada, has been added to the US Federal Permitting Dashboard for FAST-41 transparency status.
The designation, granted by the Federal Permitting Improvement Steering Council, places Angel Island alongside other critical mineral mining projects that have been listed on the dashboard since the March 2025 executive order aimed at accelerating domestic mineral production.
Arizona Gold & Silver Inc (TSX-V:AZS, OTCQB:AZASF) has announced more positive assays from its ongoing core drilling program at the Philadelphia project, including a significant high-grade gold intercept.
Hole PC25-155 intercepted 14.5 grams per ton gold over 1.52 meters within a broader interval of 4.24 g/t over 22.26 meters, the company reported on Wednesday.
C3 Metals Inc (TSX-V:CCCM, OTC:CARCF) said on Wednesday that recently completed geophysical surveys have identified large-scale anomalies coinciding with high-grade soil geochemistry at its 100%-owned Khaleesi copper-gold project in southern Peru, supporting the potential for a significant mineralized system.
The company plans to launch a 14-hole, 6,000-metre maiden diamond drilling program in the third quarter of 2025 to test both skarn and porphyry copper-gold targets.
Nevada Lithium Resources Inc (TSX-V:NVLH, OTCQB:NVLHF) released an updated Preliminary Economic Assessment (PEA) for its Bonnie Claire lithium project in Nevada highlighted by a $6.83 billion after-tax net present value (NPV) and a 32.3% internal rate of return (IRR).
The PEA outlines plans for a 61-year mine life producing an average of 62,354 tonnes of lithium carbonate and 129,533 tonnes of boric acid annually from the project's high-grade Lower Zone.
Helium One Global Ltd (AIM:HE1, OTCQB:HLOGF) shares strengthened on Wednesday after the small-cap further bolstered its coffers with a £1 million raise.
It has launched a retail offer to raise up to £1 million via the Winterflood Retail Access Platform.
Zenith Energy Ltd (LSE:ZEN, TSX-V:ZEE) has announced the acquisition of a development-stage agrivoltaic solar energy project in the Lazio region of Italy.
The project’s installed capacity will be approximately 10 MWp, and it integrates agricultural activities with solar energy production.
KEFI Gold and Copper PLC (AIM:KEFI, OTC:KFFLF) told investors it has now completed the ‘Early Works’ for the Tulu Kapi gold project in Ethiopia, clearing the way for full development.
Initial Major Works have also been certified as ready, it said.
Iluka Resources Ltd (ASX:ILU) has entered into a long-term feedstock agreement with Lindian Resources Ltd (ASX:LIN, OTC:LINIF) to secure 6,000 tonnes per annum of rare earth concentrate for 15 years. The concentrate will be sourced from Lindian’s Kangankunde project in Malawi and will supply Iluka’s Eneabba rare earths refinery, currently under construction in Western Australia.
This agreement is expected to provide around 10% of Eneabba’s total feedstock capacity and supports Iluka’s strategic objective of securing both domestic and international third-party supply. Iluka is also providing a US$20 million loan facility to assist in developing the Kangankunde project, subject to due diligence and other conditions.
Kairos Minerals Ltd (ASX:KAI, OTCQB:KAIFF) has hit a new wide gold zone — which the company’s geologists have dubbed “Monster” — at its Mt York Gold Project in Western Australia’s Pilbara, with drilling revealing significant extension of mineralisation of the Main Trend deposit near the Main Hill prospect.
In the latest drill batch, hole 25MYDD031 returned 53 metres at 1.45 g/t gold (Au) from 212 metres, including a 10-metre interval at 2.95 g/t Au. This intersection, located northwest of Main Hill, points to a previously undrilled zone of gold-bearing rock.