Prescient Therapeutics Ltd has received Fast Track Designation from the United States Food and Drug Administration (FDA) for its lead candidate PTX-100, putting the company closer to potential Accelerated Approval – a central component of its commercialisation strategy.
The designation, which applies to the treatment of adults with relapsed or refractory (r/r) mycosis fungoides – the most common subtype of Cutaneous T Cell Lymphoma (CTCL) – offers Prescient several regulatory advantages. These include increased access to the FDA and the ability to submit New Drug Applications (NDAs) on a rolling basis, expediting the review process for PTX-100.
Sovereign Metals Ltd has kicked off a suite of geotechnical drilling and investigation programs at its flagship Kasiya Rutile-Graphite Project in Malawi.
The move represents a significant milestone in the delivery of the project’s Definitive Feasibility Study (DFS), targeted for the fourth quarter of 2025.
Discovery Alaska Ltd is intensifying its search for new mineral projects as part of a broader strategy to enhance its asset portfolio and maximise shareholder value.
During the March quarter, the Australia-based explorer reviewed multiple project opportunities and undertook due diligence on assets that could complement its existing activities. The company confirmed that its efforts are aimed at identifying prospective acquisitions that would broaden its exploration footprint and unlock long-term value.
Lisata Therapeutics Inc (NASDAQ:LSTA) announced that it has entered into a research license agreement with Catalent to evaluate certepetide, its iRGD cyclic peptide candidate, using Catalent’s SMARTag antibody-drug conjugate (ADC) platform.
The research will focus on preclinical testing for diseases such as advanced solid tumors.
Blockmate Ventures Inc (TSX-V:MATE, OTCQB:MATEF) announced that its subsidiary Hivello has integrated the Swarm network into its decentralized infrastructure platform.
Swarm, a decentralized data storage and content distribution protocol, is the tenth Decentralized Physical Infrastructure Network (DePIN) now supported by Hivello.
Norsk Titanium (OTCQX:NORSF) said it is ready to support US defense needs with its proprietary Rapid Plasma Deposition (RPD) technology at the Rapid + TCT conference in Detroit last week.
Speaking at North America’s largest additive manufacturing and industrial 3D printing event, Nick Mayer, Norsk’s vice president of product management, outlined the company’s role in supplementing traditional forging and casting industries with its directed energy deposition technology.
First Phosphate Corp. (CSE:PHOS, OTCQB:FRSPF) said on Tuesday it is positioning itself as a supplier of lithium iron phosphate (LFP) battery materials to support the onshoring of American manufacturing.
The statement from the Quebec-based company comes as the US pushes to reduce reliance on China for critical technologies.
- Industrial-scale prototype shows higher yield and better charging performance at UKBIC
Ilika PLC (AIM:IKA, OTCQX:ILIKF) shares jumped 15% on Tuesday after the company announced strong results from a key production milestone for its Goliath solid-state battery programme.
Excellon Resources Inc (TSX:EXN, OTCQB:EXNRF) announced plans for a private placement offering of up to C$5 million, with prominent Canadian investor Eric Sprott participating as a lead order.
Net proceeds from the offering will be used to advance development of the Mallay Mine in Peru, as well as for working capital and general corporate purposes, the company said.
- Momentum builds for Eroxon; posts maiden profit
Shares in Futura Medical PLC (AIM:FUM, OTC:FAMDF) rose 7% in afternoon trading on Tuesday after the company reported better-than-expected full-year results and reiterated plans to expand its Eroxon product into 20 countries by the end of 2025.
Shares in OptiBiotix Health PLC (AIM:OPTI, OTC:OPBXF) jumped 10% in early trading on Tuesday after the company announced its first order from a major US weight management brand.
The AIM-listed life sciences group said the deal involves its hunger-reducing ingredient SlimBiome, which will be used in a new range of flavoured drinks. The formulation is similar to its SlimBiome Medical product and aims to tap into growing demand for natural appetite control options alongside the rise of anti-obesity drugs.
Caledonia Mining Corporation PLC (AIM:CMCL, NYSE-A:CMCL) told investors it has seen record first-quarter gold production from its Blanket mine, in Zimbabwe.
Output reached 18,671 ounces in the three months to the end of March, versus 17,050 ounces in the same period last year and beat the prior Q1 record of 18,515 ounces set in 2022.
Greatland Gold PLC (AIM:GGP, OTC:GRLGF) has upgraded its two-year outlook for the Telfer gold-copper mine and has kicked off a new study exploring options to expand production at the Havieron project.
At Telfer, annual production is Telfer is projected at 280,000 – 320,000 ounces of gold and 7,000 – 11,000 tonnes of copper through to the end of 2027.
Futura Medical PLC (AIM:FUM, OTC:FAMDF) has reported full-year results ahead of market expectations, as demand for its flagship product, Eroxon, gathers pace across international markets.
The company now expects the topical erectile dysfunction treatment to be available in 20 countries by the end of 2025, marking a significant step in its global rollout.
Ilika PLC (AIM:IKA, OTCQX:ILIKF), the UK-based developer of solid-state battery technology, has taken a step closer to commercialising its Goliath battery platform, after completing a scale-up project with the UK Battery Industrialisation Centre.
The company said it had successfully produced a batch of 10 amp-hour prototype cells using materials made at industrial scale, and that these cells outperformed those built on its in-house pilot line.
Provaris Energy Ltd has outlined robust progress in advancing its hydrogen and carbon dioxide (CO₂) transport technologies, despite geopolitical headwinds and market uncertainty that have dampened risk appetite for clean energy investments in the early months of 2025.
In a shareholder letter, the company emphasised that recent disruptions to global supply chains and regulatory frameworks have reinforced the need for flexible, regional energy solutions—areas in which Provaris’ compressed hydrogen and CO₂ shipping models are well-positioned.