Faron Pharmaceuticals researchers dose first patient in pivotal COVID-19 trial
The HIBISCUS study will be conducted across 10-15 sites in the US and will enrol 140 patients
Company
LON:FARN
Faron Pharmaceuticals is a global, clinical-stage biopharmaceutical company, focused on creating innovative cancer treatments that leverage the patient’s own immune system. The company’s lead asset bexmarilimab is currently being investigated in Phase I/II clinical trial as a potential therapy for patients with hematological cancers in combination with other standard treatments.
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The HIBISCUS study will be conducted across 10-15 sites in the US and will enrol 140 patients
The new patent covers the composition of matter of the cancer immunotherapy drug candidate and is expected to expire in 2037
The data, compiled by Dr Maija Hollmén and colleagues at the University of Turku, was published in the journal, Clinical Cancer Research
The data, compiled by Dr Maija Hollmén and colleagues at the University of Turku, was published in the journal, Clinical Cancer Research
"Bexmarilimab's ability to increase survival in patients who have exhausted all treatment options is significant," said Markku Jalkanen, Faron’s chief executive officer
It said the agreement clarifies its intellectual property position in the US
While discussions with potential partners proceed, the company has received substantial funding support from the market, putting it in a strong position to continue the progress of its pipeline
The study's data monitoring committee has suggested investigating more frequent dosing schedules in patients showing early clinical benefit
The European Investment Council Fund was the largest new investor
Traumakine has also attracted the interest of the US Department of Defense, which was revealed to be a surprise backer
Traumakine, an intravenous interferon beta-1a drug, will be given to people who have been hospitalised but who do not yet need ventilation
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Faron has been working with Kaiku Health, a data science company that uses an artificial intelligence platform to analyse patient results following treatment with cancer immunotherapies
Faron will be working directly with the 59th Medical Wing of the US Air Force
Researchers have presentation slots at the European Society of Medical Oncology Immuno-Oncology Virtual Congress
The company said it was seeing “exciting clinical activity across multiple cancer types” from bexmarilimab, formerly Clevegen
“They do support our long-held view that IFN beta-1a is likely to be ineffective when given subcutaneously."
Traumakine, an intravenously administered interferon beta -1a treatment, is part of the World Health Organisation’s global SOLIDARITY trial
Dr Petri Bono will take part in an on-demand segment at the European Society of Medical Oncology Virtual Congress
Faron is supporting global research efforts against coronavirus (COVID-19) and looks forward to receiving further data from clinical trials to support the potential use of Traumakine (IV IFN beta-1a)