Percheron Therapeutics Ltd (ASX:PER, OTC:PERCF) has released promising new preclinical data for its investigational cancer drug, HMBD-002, showing potential efficacy in the treatment of triple-negative breast cancer (TNBC), a particularly aggressive form of the disease.
The data, published in the peer-reviewed journal Cancer Research, highlights the drug’s activity in mouse models and its ability to block tumour growth in TNBC cases that express high levels of the VISTA immune checkpoint. It follows recent encouraging results for HMBD-002 in combination with radiotherapy for squamous cell cancer of the head and neck (SCCHN).
Replenish Nutrients Holding Corp (CSE:ERTH, OTC:VVIVF) said it has completed the first phase of commissioning at its Beiseker granulation facility in Alberta as it moves towards full-scale commercial production of its proprietary regenerative fertilizer products.
Initial production runs are underway at the plant, with ongoing adjustments expected over the coming weeks to meet the company’s quality and efficiency standards, Replenish said in a statement.
Stifel has reiterated its ‘buy’ recommendation and price target on Seeing Machines Ltd (AIM:SEE, OTC:SEEMF) following a trading update showing record quarterly production and strong aftermarket growth.
The broker highlighted that production of the company’s driver monitoring technology accelerated sharply.
NextSource Materials Inc. (TSX:NEXT, OTCQB:NSRCF) has signed a binding multi-year offtake agreement with Japan’s Mitsubishi Chemical Corporation (MCC) to supply graphite-based anode material for electric vehicle (EV) batteries destined for the North American market.
Under the deal, NextSource will produce intermediate anode active material (AAM) using graphite from its Molo mine in Madagascar and ship it to MCC’s plant in Japan. MCC will then process the material into finished AAM for use by a major automotive original equipment manufacturer (OEM) in North America.
North Bay Resources Inc. (OTC:NBRI) said it has completed initial test mining at its Fran Gold Project in BC, extracting high-grade ore from a massive sulphide zone that returned assay results of up to 0.5 ounces per ton of gold.
The company began development at a surface outcrop between trenches with previously reported high-grade gold mineralization, targeting a zone containing gold, copper and silver in mineralized forms such as chalcopyrite, marcasite and galena.
First Phosphate Corp. (CSE:PHOS, OTCQB:FRSPF) has announced a non-brokered private placement for gross proceeds of a minimum of $1 million to accommodate demand from an existing investor.
The offering is anticipated to consist of any combination of flow-through shares at a price of $0.50 per share and hard dollar units at a price of $0.50 per unit.
Zero Candida Ltd (TSX-V:ZCT, OTCQB:ZCTFF) announced that its common shares are now eligible for Depository Trust Company (DTC) electronic clearing and settlement services.
DTC eligibility allows for electronic clearing and settlement of Zero Candida’s common shares in the United States.
Orosur Mining Inc (AIM:OMI, TSX-V:OMI) shares traded up on Tuesday after reporting high-grade gold results from infill drilling at its Pepas prospect, in Colombia.
It is part of a programme aimed at defining a NI 43-101 compliant Mineral Resource Estimate for Pepas by the end of 2025.
European Metals Holdings Ltd (AIM:EMH, ASX:EMH, OTCQX:EMHLF) shares traded higher as a key approval was secured for the Cinovec mine.
It announced that subsidiary Geomet has been granted an updated Preliminary Mining Permit for the southern part of the Cinovec deposit by the Czech Ministry of the Environment.
‘Exceptional’ new diamond drill results from European Lithium Ltd (ASX:EUR, OTCQB:EULIF)’s Tanbreez Rare Earth Project in southern Greenland, have reinforced the project's global significance as a high-grade source of rare earth elements (REEs) and critical minerals including gallium.
Key assay results from ten previously unsampled 2010 drill holes in the Hill Deposit reveal gallium oxide (Ga₂O₃) grades ranging from 80 parts per million (ppm) to 140 ppm, total rare earth oxide (TREO) grades from 0.32% to 0.89%, and zirconium oxide (ZrO₂) from 1.01% to 3.43%. Heavy rare earth oxides (HREO) represent an average of 27% of the TREO content.
Seeing Machines Ltd (AIM:SEE, OTC:SEEMF) said on Tuesday that its driver and occupant monitoring technology is now installed in more than 3.7 million vehicles, a sharp increase of 36% over the previous quarter, as European carmakers prepare for stricter safety regulations coming into force next year.
The company designs artificial intelligence-powered systems that monitor drivers for signs of distraction or drowsiness.
In the wake of NATO’s historic decision to increase its defence spending target to 5% of gross domestic product (GDP), the global defence sector is experiencing a major shift — and Australian companies are in a strong position to benefit.
With geopolitical tensions, particularly from the Russia-Ukraine war, consistently dominating headlines, the growing defence focus is expected to trigger a surge in demand for advanced military technologies. From drones and cyber capabilities to autonomous systems, the need for next-gen defence tech is becoming more pressing, and local firms are already preparing to play a crucial role in meeting this demand, with several major developments announced this week.
Recce Pharmaceuticals Ltd (ASX:RCE, OTC:RECEF) will present new data on its lead synthetic anti-infective, RECCE® 327 (R327), at the 2025 Military Health System Research Symposium (MHSRS) in Florida, United States. The presentation will be delivered as a poster and in-person oral session and will highlight R327’s activity against a suite of high-priority bioterrorism pathogens.
The session, titled Optimising Medical Readiness, MHS Resilience, & Biodefense across R&D for Future Pandemics, will feature Recce’s abstract, RECCE® 327: A Novel Countermeasure for High-Priority Bioterrorism Pathogens. It showcases promising laboratory data against Category A and B biological threats identified by the US Centers for Disease Control and Prevention (CDC), including anthrax, tularemia, glanders, melioidosis and plague.