Imugene granted HER-Vaxx immunotherapy patent in the US; shares rise 12%
The patent provides method of composition and method of use protection to 2036.
Company
ASX:IMU
Imugene Ltd is a clinical stage immuno-oncology company developing a range of new treatments that seek to activate the immune system of cancer patients to identify and eradicate tumours. The company's unique platform technologies seek to harness the body’s immune system against tumours, potentially achieving a similar or greater effect than synthetically manufactured monoclonal antibody and other immunotherapies. Imugene is supported by a leading team of international cancer experts with extensive experience in developing new cancer therapies with many approved for sale and marketing for global markets.
224 stories · page 9 of 12
The patent provides method of composition and method of use protection to 2036.
Dr. Auer heads a research laboratory and is the principle investigator in related clinical trials.
The placement raised A$24.6 million and was well supported by existing investors and new sophisticated and institutional investors.
Paul Hopper is an Australian biotech entrepreneur who has been associated with a number of biotechnology companies.
The company’s securities are in a trading halt until Monday, December 2, or when an announcement is made to the market.
CF33 is a highly potent, chimeric oncolytic poxvirus – a poxvirus refers to a large group of DNA viruses that cause smallpox and similar infectious diseases in vertebrates.
The company’s vision is to help transform and improve the treatment of cancer and the lives of the millions of patients who need effective treatments – this vision is backed by a growing body of clinical evidence and peer-reviewed research.
“We are delighted to be able to complete the acquisition of Vaxinia Pty Ltd and City of Hope licence of such a promising next-generation oncolytic virus,” says MD and CEO Leslie Chong.
Imugene is planning two separate Phase 1 clinical trials in 2020 to test a CheckVacc construct and a Vaxinia construct of the CF33 oncolytic virus.
The grant focuses on the area of gastric cancer, a disease that disproportionately affects US military service members, veterans, and their beneficiaries.
Two separate Phase 1 clinical trials will be conducted in 2020 to test a CheckVacc construct and a Vaxinia construct of the oncolytic virus.
A pioneer in the operating room and in the laboratory, Dr Fong, The Sangiacomo Family Chair in Surgical Oncology and chair of The City of Hope Dept of Surgery, is a recognised expert in liver and pancreatic cancer.
Inventor Ursula Wiedermann and investigators Tanios Bekaii-Saab and Joshua Tobias presented findings from early study of vaccines for gastric, colon and breast cancers.
A phase-one clinical trial in 30 patients with advanced tumours is expected to start in 2020 across a number of US cancer centres.
HER-Vaxx is a B-cell peptide cancer vaccine designed to treat tumours in gastric, breast, ovarian, lung and pancreatic cancers.
Results were presented at the ASCO annual meeting in Chicago, which attracts over 40,000 cancer specialists.
The company finished the March quarter with $21 million in the bank.
Imugene’s HER-Vaxx is a B-cell peptide cancer vaccine designed to treat tumours that over-express the HER-2/neu receptor.
Dr. Lesley Russell brings extensive pharmaceutical experience to the board including a number of cancer therapy collaborations with Teva Pharmaceuticals.
The company is currently fully funded in supporting all clinical research programs.