AstraZeneca says ALXN1840 phase III trial in Wilson disease meets primary endpoint
ALXN1840, a potential new once-daily, oral medicine, demonstrated three times greater copper mobilisation than standard treatments
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LON:AZN
AstraZeneca is one of the world's leading pharmaceutical companies, with a broad range of medicines designed to fight disease. AstraZeneca has over 67,000 empolyees and operates in over 100 countries with growing presence in important emerging markets.
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ALXN1840, a potential new once-daily, oral medicine, demonstrated three times greater copper mobilisation than standard treatments
A phase III trial showed that Forxiga reduced the risk of worsening of renal function, onset of end-stage kidney disease or risk of cardiovascular or renal death by 39%
Reports have suggested the plan is to start vaccinations ahead of the September return to school.
The trial of the group's Ultomiris treatment was halted due to lack of efficacy
The company's AZD7442 drug reduced the risk of developing symptomatic COVID-19 by 77% compared to placebo
“Both of these vaccines, at two doses, are still doing really well against Delta"
“We see Astra’s sector discount unwinding, as the Alexion acquisition demonstrates continued strong top-line growth, coupled with significant operating margin expansion and increased free cash flow generation,” JP Morgan Cazenove said in it
The investment bank resumed coverage with an ‘overweight’ recommendation and a 9,800p target price
The group also announced positive final-stage trial results for Enhertu on breast cancer patients
It’s time we recognised the quality that other countries see in the UK, and back ourselves by investing more money"
Trial patients experienced a reduction in organ damage and needed fewer oral corticosteroids, which can cause side effects
"Is the vaccine business a sustainable business for AstraZeneca for the next five or 10 years/"
In the first half of the year, the COVID-19 vaccine delivered sales twice the consensus view
The group said the efficacy and safety of Ultomiris in children and teens are consistent with what has been demonstrated in adults.
The approval was based on positive results from a phase III trial where Imfinzi showed improvement compared to chemotherapy alone
Before the committee’s meeting, the FDA issued a briefing document that said the drug’s safety in CKD patients was the main issue
Rare diseases "represent a high-growth opportunity with rapid innovation and significant unmet medical needs", the company said
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