Antibiotic resistance is tightening its grip on global healthcare, but the pipeline of truly new treatments remains thin.
That imbalance — rising need, limited innovation — has become a defining theme in infectious disease biotech. And it’s one that Recce Pharmaceuticals Ltd (ASX:RCE, OTC:RECEF) Ltd is aiming to tackle with a new class of synthetic anti-infectives now advancing through late-stage trials.
Antipa Minerals Ltd (ASX:AZY) has delivered a substantial upgrade to the Mineral Resource Estimate at its 100%-owned Minyari project in Western Australia, growing the resource to 3.6 million ounces gold equivalent and boosting confidence in the core development inventory.
The updated estimate contains 2.9 million ounces of gold, 91,000 tonnes of copper and 880,000 ounces of silver, with the increase strengthening the case for Minyari as a large-scale standalone gold-copper development in the Paterson Province.
Shares in Greatland Resources Ltd (AIM:GGP, OTC:GRLGF, FRA:G8G, ASX:GGP), the gold and copper miner, are up a further 13% to 665.2 in London trading on Wednesday as investors continued to digest landmark resource update at its Telfer operation in Western Australia.
The gains have been amplified by a broader re-rating of precious metals stocks, with gold rising 1.8% as conciliatory rhetoric from Iran eases tensions in the Middle East.
Manhattan Gold Corp Ltd (ASX:MHC, OTC:MHTZF, FRA:32U) has expanded its Hook Lake Project footprint by securing six new mineral claims covering an additional 81km² within the Kaminak Greenstone Belt, located about 30 kilometres west of its existing project area.
The move materially increases the company’s exposure to a highly prospective and underexplored gold belt, with the new ground hosting what has been described as the largest gold-in-till anomaly in the region. Importantly, this anomaly remains untested by drilling, highlighting the potential for new discoveries.
European Lithium Ltd (ASX:EUR, OTCQB:EULIF) extended its on-market share buy-back program, with the current buy-back closing on March 31, 2026 and a new six-month program set to run from April 15 to October 15, 2026.
The extension will operate within the Corporations Act’s 10/12 limit, allowing the company to repurchase up to 10% of its issued capital without shareholder approval. Shares acquired under the program will be cancelled, reducing total shares on issue. The company noted that the scale and timing of purchases will depend on prevailing market conditions, with Evolution Capital continuing as broker.
Bioxyne Ltd (ASX:BXN, FRA:PR8) has signed a manufacturing agreement with Aurora Cannabis Inc (TSX:ACB, NASDAQ:ACB), giving the Australian company a supply deal with one of the world’s largest medical cannabis producers and broadening its reach across regulated international markets.
The agreement, signed through Bioxyne’s wholly owned subsidiary Breathe Life Sciences (BLS), initially covers the manufacture of GMP-certified medicinal cannabis oils for the Australian market, with first deliveries already completed.
Lotus Resources Ltd (ASX:LOT, FRA:7D0) has secured acceptance from Orano Chimie-Enrichissement for uranium ore concentrate from its Kayelekera mine in Malawi at Orano’s conversion facility in Malvesi, France, marking a key step toward first sales from the restarted operation.
The approval follows months of work with Orano to optimise and qualify the Kayelekera product through an iterative process. Orano has agreed to accept the material, with independent laboratory testing results to be provided by Lotus as a condition for initial shipments.
Lumos Diagnostics Holdings Ltd (ASX:LDX, OTC:LDXHF) has received its largest purchase order to date for the FebriDx® rapid respiratory infection test, with US exclusive distributor PHASE Scientific lodging an order valued at US$1.3 million.
The order marks an early commercial outcome from the expanded US opportunity now available to FebriDx.
Lindian Resources Ltd (ASX:LIN, OTC:LINIF) has secured firm commitments to raise A$100 million through an institutional placement, strengthening its balance sheet and accelerating development across its flagship Kangankunde rare earths project and downstream processing strategy.
The placement, priced at A$0.75 per share, was strongly supported by domestic and offshore institutional investors and was oversubscribed, signalling continued investor appetite for near-term rare earths producers.
St George Mining Ltd (ASX:SGQ, FRA:S0G, OTC:SGQMF) is looking to reshape how niobium is produced at its flagship Araxá project in Brazil, signing a strategic alliance with US-based Boston Metal to trial a potentially game-changing processing technology.
The memorandum of understanding (MoU) will see the companies collaborate on testing Boston Metal’s molten oxide electrolysis (MOE) technology on niobium from Araxá, with the aim of improving production efficiency, lowering costs and reducing environmental impact.
American Rare Earths Ltd (ASX:ARR, OTCQX:ARRNF) is fast-tracking development at its flagship Halleck Creek project in Wyoming, advancing plans for a pilot plant program aimed at producing pre-production rare earth concentrate as it moves closer to potential commercialisation.
The company has engaged veteran metallurgical engineer Jaye T. Pickarts to lead the pilot plant process, bringing more than four decades of experience across mine development, mineral processing and rare earth demonstration facilities. His appointment is expected to support the integration and optimisation of the pilot circuit as ARR looks to de-risk the next stage of development.
Imugene Ltd (ASX:IMU, OTC:IUGNF, FRA:ILA) will present data from its lead cancer therapy candidate azer-cel in an oral presentation at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, marking a high-profile milestone for the company.
The clinical-stage immuno-oncology company said the azer-cel data had been selected for oral presentation at the conference, to be held from May 29 to June 2, 2026. ASCO is regarded as one of the world’s leading oncology meetings, with more than 8,500 abstracts reviewed this year by the Scientific Program Committee.
Aruma Resources Ltd (ASX:AAJ) has sharpened its exploration focus at the Tillex Copper-Silver Project in Ontario, with a new electromagnetic (EM) survey confirming strong conductive targets that extend both the depth and strike potential of the high-grade system.
The fixed loop time domain electromagnetic (FLTDEM) survey has identified two significant conductors, reinforcing Tillex as a growing copper-silver opportunity and providing clear targets for an imminent maiden drilling program.