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The Markets
by Proactive
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Archive

Small cap wrap: Medicus Pharma, C3 Metals, Protalix BioTherapeutics…

Orthocell Ltd (ASX:OCC, OTC:ORHHF) has appointed UK medical device distributor LEDA Orthopaedics as the exclusive in-country distributor for Remplir™, marking an early commercial step ahead of the company’s planned entry into the UK and broader European nerve repair market.

The appointment follows Orthocell’s December 2025 submission to the British Standards Institution seeking approval to sell Remplir in the UK and EU, a combined market the company values at US$750 million and estimates accounts for around 500,000 peripheral nerve repair procedures each year. Approval remains on track for a decision in Q3 FY26.

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St George Mining Ltd (ASX:SGQ, FRA:S0G, OTC:SGQMF) has appointed Brazilian resource geologist Carla Grasso as principal geologist for its Araxá rare earths-niobium project in Minas Gerais, adding in-country technical leadership as it advances economic studies for a potential mining operation.

Grasso will be based in the city of Araxá and will take a lead role in mine planning for the 100%-owned project, with responsibilities spanning mineral resource modelling, reserve estimation, grade control, pit optimisation and geometallurgical assessment. Her role also includes overseeing resource reporting, coordinating geo-metallurgical programs and supporting both short and long-term mine planning.

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The S&P/ASX Small Ordinaries Index (ASX: XSO) fell sharply in the latest session, closing at 3,463.20, down 131.60 points (3.66%), while the index has declined 300.60 points (7.99%) over the past five days, reflecting broader weakness across the small-cap segment of the Australian market.

The decline hasn't stopped companies releasing operational and corporate updates across the healthcare, resources and exploration sectors. You can read about the following and more throughout the door.

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1911 Gold Corp (TSX-V:AUMB, OTCQB:AUMBF, FRA:2KY) said on Monday it has drawn the first $15 million tranche of a $30 million secured credit facility arranged with Auramet International to advance development at its True North Gold Project in Manitoba.

The initial funding follows a loan agreement signed on February 19 and will be used to support operational milestones at the project, including the purchase of mining equipment, underground development at the True North mine and the installation of a new crushing circuit at the mill.

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Noble Capital Markets analysts have reiterated their 'Outperform' rating on Bit Digital Inc (NASDAQ:BTBT) after the company released its February Ethereum treasury and staking data.

The firm maintained its $5.50 price target on the company's shares, implying upside from current levels of about $1.60, citing the company’s strategic positioning in Ethereum (ETH) and related holdings.

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Montero Mining and Exploration Ltd (TSX-V:MON, OTC:MXTRF) said on Monday it has completed a detailed exploration and data compilation program at its Potrero gold project in Chile’s Maricunga Belt, a prolific mining district in northern Chile.

The program, which incorporated advanced analytics and machine learning techniques, aimed to refine the geological and structural understanding of the project and assess its potential for gold mineralization at depth, the company said.

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Protalix Biotherapeutics Inc (NYSE-A:PLX, FRA:PBDA) announced that the European Commission has approved a new dosing regimen for pegunigalsidase alfa for adults with Fabry disease who are stable on enzyme replacement therapy (ERT), triggering a $25 million regulatory milestone payment from partner Chiesi Global Rare Diseases.

The approval allows eligible patients to receive the therapy at a dose of 2 mg/kg every four weeks, instead of the previous every-two-weeks schedule. According to the companies, the change could reduce the treatment burden for patients, their families and healthcare systems by extending the interval between infusions.

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Lisata Therapeutics Inc (NASDAQ:LSTA, FRA:8NE), a clinical-stage pharmaceutical company developing therapies to treat advanced solid tumors and other serious diseases, announced that it has agreed to be acquired by privately held Kuva Labs.

Under the terms of a definitive agreement, Kuva will launch a tender offer to purchase all outstanding Lisata shares for $5 per share in cash at closing, plus one contingent value right (CVR) per share.

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Northstar Gold Corp. (CSE:NSG) announced that it has closed the first tranche of its previously disclosed non-brokered private placement, raising gross proceeds of $558,000.

The Vancouver-based company issued 9.3 million units at $0.06 per unit. Each unit consists of one common share and one common share purchase warrant, with each warrant exercisable at $0.075 per share for a period of 60 months.

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G Mining Ventures Corp (TSX:GMIN, OTCQX:GMINF, FRA:W97) said its largest shareholder, La Mancha Investments, will invest about C$427 million to maintain its ownership in the Canadian gold developer at 19.9%, reinforcing its long-term backing of the company.

The investment comes as the shareholder exercises a contractual top-up right under an investor rights agreement with G Mining Ventures that allows it to maintain a stake of up to 19.9%.

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C3 Metals Inc (TSX-V:CCCM, OTC:CUAUF) said on Monday that new geochronology results from its Khaleesi copper project in southern Peru show the mineralization formed about 35.8 million years ago, placing it within the same age range as several major copper deposits in the Andahuaylas-Yauri belt.

The exploration company said the age-dating program suggests the Khaleesi system developed during a key mineralizing period for porphyry and skarn deposits in the region, which typically formed between about 40 million and 30 million years ago.

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Medicus Pharma (NASDAQ:MDCX) said on Monday that new analysis of data from a mid-stage clinical trial of its SkinJect microneedle therapy showed encouraging results in treating basal cell carcinoma, the most common form of skin cancer.

The Medicus Pharma Ltd said the Phase 2 SKNJCT-003 study evaluating its SkinJect microneedle delivery system achieved 73% clinical clearance and 40% histological clearance in patients treated with a 200-microgram dose by Day 57, the strongest treatment response seen in the trial.

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Arc Minerals Limited (AIM:ARCM, OTC:ACMNF, FRA:DFYA) has now kicked off a geophysical work programme at its Virgo Project in Botswana, as the explorer steps up efforts to map a key copper-bearing contact zone across its PL135/2017 licence.

The company told investors that field camp preparation is underway and teams have been mobilised, with 295 line kilometres of ground-based magnetic surveying due to begin this week.

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HeLIX Exploration PLC (AIM:HEX, OTCQB:HHEXF) has secured its first helium transport trailer, a practical step toward commercial production at its Rudyard project in Montana as disruption in Qatar squeezes global supply.

The AIM-listed group told investors it has signed a lease for a ten-cylinder jumbo tube trailer with capacity to carry 156,300 standard cubic feet of compressed helium at a working pressure of 2,669 PSI.

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Active Energy Group PLC (AIM:AEG, OTCQB:ATGVF), the AIM-listed renewable energy and digital infrastructure company, has said its first facility in the United Arab Emirates will be handed over a little later than planned after permitting delays, the Ramadan period and regional disruption caused by the recent Middle East crisis pushed back its commissioning schedule.

The company said infrastructure handover at its 8-megawatt energy and digital infrastructure site, its first in the Gulf Cooperation Council region, is now expected by the end of April 2026.

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St George Mining Ltd (ASX:SGQ, FRA:S0G, OTC:SGQMF) will join the S&P/ASX All Ordinaries Index from the start of trading on March 23, 2026, marking another step in the company’s rapid rise following its acquisition of the Araxá Rare Earths-Niobium Project in Brazil.

The inclusion places St George among the 500 largest companies on the ASX by market capitalisation and is expected to lift the company’s visibility among a broader pool of investors, including index-tracking funds and institutions.

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Nova Minerals Ltd (ASX:NVA, NASDAQ:NVA, OTC:NVAAF, FRA:QM3) has reported further high-grade gold results from surface sampling near the RPM prospect at its Estelle Gold and Critical Minerals Project in Alaska, highlighting new exploration targets ahead of planned drilling in 2026.

The company said field observations and assay results from its 2025 exploration program have identified gold anomalies along the northern extension of the RPM ridgeline and in an area 2 to 3 kilometres to the west.

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