PDS Biotechnology, a portfolio company of NetScientific PLC (AIM:NSCI), has announced an update on its clinical strategy alongside its full-year financial results for 2023.
PDS's approach was to combine PDS01ADC with Versamune, which demonstrated a three-year survival rate of 75% and an overall response rate of 75% in a trial for advanced head and neck cancer.
atai Life Sciences (NASDAQ:ATAI, ETR:9VC) has hailed positive results from its investee Beckley Psytech’s Phase 2a study of its novel DMT formulation BPL-003 in patients with treatment-resistant depression.
The biopharmaceutical company said during the open-label study, a single 10mg dose of BPL-003 – a novel, synthetic, patent-protected benzoate salt formulation of 5-MeO-DMT (mebufotenin) – was administered intranasally along with psychological support and induced a rapid antidepressant response in 55% of patients the day after dosing.
Mosman Oil and Gas Ltd (AIM:MSMN) has reported its first-half results and expressed an optimistic outlook for the second half with a refreshed board of directors and costs reduced.
For the six months to 31 December 2023, revenue came to A$533,794 compared to A$936,187 last time as production at the Stanley site in Texas, USA, was affected by downtime due to reconfiguration of production equipment and weather conditions in December.
Critical Mineral Resources PLC (LSE:CMRS) has updated investors on its Ifri project, in the Anti-Atlas region, where initial work has revealed significant potential for copper, silver, and gold mineralisation.
Initial prospecting efforts have demonstrated the presence of copper and silver in multiple shear zones and quartz vein structures, with certain areas also indicating the presence of gold.
Accesso Technology Group PLC (AIM:ACSO, OTC:LOQPF) has signed a landmark agreement with Saudi Entertainment Ventures (SEVEN), a wholly owned subsidiary of the Saudi Arabia Public Investment Fund (PIF).
In November 2022, SEVEN unveiled plans to introduce 21 cutting-edge entertainment destinations across 14 cities, featuring over 150 attractions, diverse dining outlets, local and international retail outlets that complement the overall entertainment ecosystem that SEVEN is spearheading.
Empire Metals Ltd (AIM:EEE) has appointed two members to the development team as it introduced a 2024-25 project development plan for its Pitfield project in Western Australia, identifying key milestones in the next 12 months.
The company, which is currently logging and sampling the drill cores from recently completed diamond drilling as well as carrying out a third phase of reverse circulation drilling with two rigs on site drilling 40 more holes, said the achievement of each of the milestones in the development plan will “incrementally de-risk the project and together will unlock significant value”.
Zephyr Energy PLC (AIM:ZPHR, OTCQB:ZPHRF) has laid out its plans for the Salt Wash Field helium project, located in the vicinity of its Paradox oil and gas project.
The AIM-quoted firm is to acquire at least 75% of Salt Wash, which was formerly an oil and gas operation with by-product helium volumes.
Endeavour Mining PLC (LSE:EDV, TSX:EDV, OTCQX:EDVMF) hailed an 11th consecutive year of achieving or beating production guidance as it unveiled annual earnings (EBITDA) of $1.05 billion and shareholder returns of $266 million.
While the full-year earnings figure was down 8% year on year, the Africa-focused gold miner delivered $292 million in earnings, up 11%, at an all-in cost of $947 an ounce.
Endeavour Mining PLC (LSE:EDV, TSX:EDV, OTCQX:EDVMF) has announced the completion of an investigation initiated after the dismissal of its former chief executive, Sébastien de Montessus.
It was launched to scrutinise certain financial transactions following his termination and was concluded without the need for a restatement of the company's historical financial statements, with no material impact on 2023 accounts, which received an unmodified audit opinion.