Anti-microbial resistance (AMR) and the decreasing effect of antibiotics today are a significant and growing global problem, according to a large study of the impact of AMR published in the Lancet had concluded.
The study found that more than 1.2mln people died worldwide in 2019 from infections caused by bacteria resistant to antibiotics, in other words infections that were previously treatable but now the bacteria that cause them have become resistant to treatment.
Caledonia Mining Corporation PLC (AIM:CMCL, NYSE-A:CMCL) said that chief operating officer Dana Roets has joined the board with immediate effect.
Having been in the COO role since 2013, he will continue in this role following his appointment, the company said in a statement.
Open Orphan PLC (AIM:ORPH, OTC:OPORF) said researchers at its hVIVO subsidiary inoculated the first group of volunteers as part of its first controlled human malaria infection challenge study.
The team will assess the standard of care antimalarial treatments against plasmodium malaria.
Arecor Therapeutics PLC (AIM:AREC) said the ‘momentum continues’ across its portfolio of owned and partnered assets as it flagged the start of a US phase I trial of its lead asset.
Investors were told that it had begun its clinical assessment of AT247, an ultra-rapid insulin that will be delivered by continuous subcutaneous infusion via insulin pump.
Tirupati Graphite PLC (LSE:TGR, OTCQX:TGRHF) said it achieved a milestone with its new "transformational" technology for processing flake graphite.
The unique Column Flotation System (CFS) will "significantly improve performance" of the company's primary graphite and downstream specialty graphite production processes, Tirupati said in a statement.
Ilika PLC (AIM:IKA, OTCQX:ILIKF) said it continued to develop and progress its Stereax and Goliath product lines as the pioneer in solid-state battery technology ended its half year with £27.7mln of cash and cash equivalents.
The company opened its Stereax solid-state battery manufacturing facility in Chandlers Ford in December, allowing it to manufacture its micro batteries designed to power medical devices and industrial wireless sensors (IIoT) in hostile environments.
Ora Banda Mining Ltd (ASX:OBM) has made a significant stride forward with its operational performance at the Davyhurst Gold Project in the Eastern Goldfields region of Western Australia during the December 2021 quarter.
During the period, Ora ran open pit and underground mining operations at Riverina, Missouri and Golden Eagle; with the Golden Eagle mine completing production as planned at quarter-end.
Altech Chemicals Ltd (ASX:ATC)’s 75%-owned German subsidiary, Altech Industries Germany GmbH (AIG), has taken up the option to buy a ~14-hectare industrial site in Saxony, Germany.
ATC intends to build a 10,000 tonnes per annum high purity alumina (HPA) battery materials coating plant on site.
IXICO PLC has confirmed that an open-label extension study in Huntington's disease that it provided neuroscience support for will close in May. This will result in a £300,000 reduction of revenues. In the update, the group said its order book stands at £12.6mln and added it has a strong pipeline of potential new business.
Cloudbreak Discovery PLC told investors that Kyle Hookey has stepped down as non-executive director of the company with immediate effect but will continue as a key advisor. Kyler Hardy, president and CEO, said: "Kyle has been a great asset to Cloudbreak as a director and will continue to be involved with an integral advisory role with the company. In the coming months, we will be seeking a replacement director whose skill set will allow Cloudbreak to continue with its growth and execution of its business plan."
Bradda Head Lithium Ltd announced that its shares will cross-trade publicly on the US OTCQB Market under the ticker BHLIF with effect from market open in the US today. Chief executive Charles FitzRoy said: "The company is seeking to encourage the significant interest that our Arizona projects have generated internationally with the commencement of trading of our shares on the OTCQB. The US has significant interest in lithium as a commodity and we hope that the visibility we gain will further broaden our shareholder base and increase shareholder demand in one of the major lithium markets."
Versarien PLC said it will hold an investor event on 2 February 2022, hosted by CEO Neill Ricketts at Versarien's production facilities in Longhope, Gloucestershire. This will allow participants to have the opportunity to learn more about the company's Cementene graphene enhanced concrete, the materials technology and how the company can provide solutions to applications partners for achieving Net Zero, together with observing a practical demonstration of Cementene's use. In order to attend investors should apply via https://www.eventbrite.co.uk/e/247170402327, with 40 tickets allocated on a first come, first served basis.
4D pharma PLC said it will host a virtual key opinion leader event to review previously disclosed positive topline results from Part A of its Phase I/II trial of MRx-4DP004 for the treatment of asthma and to discuss the asthma treatment landscape. The event will take place on 27 January 2022. The event will feature presentations from 4D pharma management and Professor Chris Brightling of the National Institute for Health Research (NIHR), who was principle investigator of the Phase I/II trial. A live webcast of the event will be available on the reports and presentations section of the 4D Pharma website.