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Evgen Pharma CEO hails pre-clinical data from lead drug in glioma and glioblastoma models

Work carried out in collaboration with an unnamed but prominent European university showed tumour shrinkage and significantly extended survival times

Evgen Pharma PLC -

Evgen Pharma PLC (LONEVG) chief executive Dr Huw Jones has said he is excited by “compelling new data” for lead compound SFX-01 in pre-clinical models of glioma and glioblastoma.

Work carried out in collaboration with an unnamed but prominent European university showed tumour shrinkage and significantly extended survival times.

SFX-01 was also found to substantially increase the therapeutic effect of radiotherapy in these models.

“The positive tolerability profile of SFX-01 makes it a viable option for use in addition to current treatments,” said CEO Jones in a statement.

“Our plan is to expand upon these pre-clinical data in this and new collaborations, and start the process of designing an appropriate Phase II clinical trial."

People with glioma, a blanket term for glial tumours that affect the brain, have severely limited therapeutic options.

Evgen is developing medicines based on sulforaphane, a sulfur-rich compound found in vegetables such as broccoli, bok choy, and cabbage.

Its core technology is Sulforadex, a method for synthesising and stabilising the naturally occurring compound.

The group's lead product is SFX-01, a patented composition of synthetic sulforaphane and alpha-cyclodextrin.

Last year Evgen successfully completed a phase II trial of its drug in women with certain forms of advanced breast cancer.

Quick facts: Evgen Pharma PLC

Price: 8.295 GBX

AIM:EVG
Market: AIM
Market Cap: £22.8 m
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