4D pharma plc (LON:DDDD) has said results of a trial using its Live Biotherapeutic in combination with an established cancer drug called a checkpoint inhibitor “far exceeded” the threshold for success set out before the study began. MRx0518 was used alongside Merck & Co’s Keytruda to treat 12 ‘end of line’ patients with either advanced metastatic renal cell carcinoma or metastatic non-small cell lung cancer. Five people, or 42% of the group, experienced a clinically meaningful benefit from the two drugs. This was well ahead of the success threshold of 10% agreed at the outset of the phase I/II trial. Three patients enjoyed what’s called a partial response to the combination with tumour shrinkage of 30% or greater; in the other two the disease remained stable. The median duration of treatment for the five patients experiencing the clinical benefit from the regimen is now 13.2 months. The treatment itself was well tolerated with no serious adverse effects.
EQTEC PLC (LON:EQT) said it has signed an equipment sale and services deal with German EPC firm ewerGy relating to a waste gasification project in Larissa in Greece, the country’s first waste gasification plant. The AIM-listed waste-to-energy technology firm said the deal involves the sale of equipment and engineering & design services to ewerGy worth €2mln, which will be paid in stages over 18 months. EQTEC also said the financial close for the Larissa plant has occurred with the first milestone payment of €200,000 expected to be received in September this year.
Iofina PLC (LON:IOF) has said it is making “continued positive progress” regarding its debt refinancing with a new US lender. The iodine maker said the necessary internal approvals have now been obtained by the lender and the transaction is in the final legal documentation phase, with the specifics of the transaction to be detailed to the market once documentation is complete and finalised. General terms include a term loan as well as a revolving line of credit which will allow Iofina to fully pay current debt holders.
Blue Star Capital PLC (LON:BLU) has said that SatoshiPay, the payment company in which it has 27.7% stake, has processed over €1mln of transactions for publishing clients. German giant Axel Springer has been an early adopter of the technology as has Börsenmedien's leading German retail investor magazine Der Aktionär. The blockchain-enabled clearing platform has allowed readers to make micro-payments for premium content rather than being forced to take out subscriptions.
Panther Metals PLC (LON:PALM) said it has identified a structural zone at its Marrakai gold project in Australia’s Northern Territory. An assessment of available ground and airborne geophysical data has confirmed the presence of a 3.6 kilometre (km) by 0.5km structural zone that Panther believes might control the location of mineralisation within the project. Identified gold prospects at Steve's Hill, John's Reef Gold and Chins are closely associated to this NE magnetic trend according to the data, Panther added. Previously unrecognised high-priority magnetic targets were also present in the southern portion of the exploration licence that showed a similar geophysical response to Steve's Hill.
Emmerson PLC (LON:EML) has announced the findings of a socio-economic study which confirms that the Khemisset potash project in Morocco will provide significant benefits at local, regional and national levels. The study, authored by economics professor Sallem Koubida, estimates the mine project will lift local GDP per capita by around 40%. It will create 2,385 direct and indirect jobs during construction, the study estimates, while the operational mine will create 1,500 jobs - comprising 760 direct employees - with the company aiming to fill 90% of roles with people from the Khemisset area and surrounding communities.
Union Jack Oil PLC (LON:UJO) has noted a resolution of the dispute between its fellow partners in the PEDL253 licence, which hosts the Biscathorpe project in Lincolnshire. A payment from Humber Oil & Gas has been received by Egdon Resources PLC (LON:EDR) following a confidential settlement agreement, agreed in June. Back then, Humber and Egdon had said they looked forward to co-operating in the future in the development of the licence.
ADM Energy PLC (LON:ADME) said it has raised £672,500 with the funds set to be used to support its deal to acquire an additional stake in the OML 113 asset in Nigeria. It will allow the company to satisfy the £500,000 cash payment in the agreed acquisition from EER, giving the company an additional 2.25% interest in OML 113 taking its stake to 5%, while the ‘profit interest’ increases to 9.2% from 5%. "This funding brings us a step closer to completing our first deal under the company's new leadership, increasing ADM's position in the highly strategic asset of OML 113,” said Osamede Okhomina, ADM chief executive.
ADM Energy also said it had received notification for the exercise of warrants from participants in the £200,000 loan facility announced on April 27, 2020. The exercise of warrants is over 5,208,333 ordinary shares of 1 pence each in the capital of the company at a price of 2.4p per share. The proceeds of the warrant exercise amounts to £125,000 and have been applied against the original loan amount from the lenders. The company has also issued an additional 416,667 ordinary shares at a price of 2.4p per share to one of the lenders to settle the £10,000 interest accrued on the lender's original loan. Following the exercise of warrants, £175,000 of the £200,000 loan facility has now been repaid.
FastForward Innovations Limited (LON:FFWD) said it has a “great opportunity to scale up” and focus its capital on the areas of life sciences, longevity, healthcare and cannabinoid therapies as it reported its full-year results. In a statement, chief executive Ed McDermott said over the year to March 31, 2020, that a “large portion” of the company’s investments “have continued to make positive advances and reach significant milestones in their development” and that going forward the group was “well-positioned to deliver value over the short-to-medium term” and reach a share price that was “more reflective” of the company’s net asset value (NAV), which at the end of the period stood at around £14.2mln compared to £19.07mln in the prior year.
KR1 PLC (KR1) said it will have a share of “the pick of the best seed-stage opportunities in the Ethereum space” after becoming a member of the MetaCartel Ventures decentralised autonomous organisation.
Ashley House PLC (LON:ASH) said it will proceed with a proposed merger with Midlands housebuilder Piper Homes after creditors and shareholders approved a company voluntary arrangement (CVA) over its assets.
TomCo Energy plc (LON:TOM) confirmed that good progress is being made with proposed upgrades to Petroteq's oil sands plant (POSP) at Asphalt Ridge, in Utah. It notes an announcement from Petroteq Energy Inc communicated details released last week by TomCo and Quadrise respectively. Greenfield Energy LLC, a joint venture between TomCo and Valkor, last week announced it is advancing into Phase 1 with its project at POSP.
Karelian Diamond Resources PLC (LON:KDR) has said that it was informed on Tuesday that Steve Coomber now holds 2,300,000 ordinary shares of €0.00025 in the company, equal to approximately 4.30% of the current issued share capital and voting right.
City Pub Group Plc (LON:CPC) said it was notified that Clive Watson, the company's executive chairman purchased 20,000 ordinary shares of 1 pence in the capital of the company on August 24, 2020, at a price of £0.6375 per ordinary share and 35,000 ordinary shares on August 25, 2020, at a price of £0.665 per ordinary share. Following these purchases, it added, Watson is beneficially interested in 3,323,156 City Pub ordinary shares, representing approximately 3.20% of the company's issued share capital.
Integumen PLC (LONLSKIN) said it has received notification from multiple holders to exercise warrants over 1,928,573 shares in the company at an exercise price of 2p each, giving it an aggregate consideration with a cash value of £38,571.46.
IXICO PLC (LON:IXI), the data analytics company delivering insights in neuroscience, has said a recording of the online company presentation, delivered by Giulio Cerroni, its chief executive officer, and Grant Nash, its chief finance officer, on Tuesday August 25, 2020, surrounding the company's recent trading update, is now available to watch back on the Investor Meet Company platform. The Q&A has also been published following the meeting. Investors can sign up to Investor Meet Company for free and add to meet IXICO via the following link, which will take you to the recording of the presentation and the Q&A: https://www.investormeetcompany.com/ixico-plc/register-investor. No new price-sensitive information was disclosed as part of the presentation.
Solo Oil PLC (LON:SOLO), the AIM-listed investing company targeting attractive production and development opportunities within the European energy market, has said it intends to report its audited annual results for the year ended December 31, 2019, on Tuesday, September 1, 2020.
Alliance Pharma PLC (LON:APH), the international healthcare group, has said it will announce its results for the six months ended June 30, 2020, on Tuesday, September 22, 2020. A conference call for analysts will be held at 10.30am on September 22, 2020; analysts who require dial-in details, please contact Buchanan at [email protected]. A recorded webcast of the analyst conference call, including investor presentation slides, will be made available during the afternoon of September 22 at this link: https://webcasting.buchanan.uk.com/broadcast/5f3fbab0b14d87262643a98b. The recorded webcast will also be made available at the investor section of Alliance's website, https://www.alliancepharmaceuticals.com/investors/