viewSareum Holdings PLC

Sareum Holdings agrees licensing deal with Shanghai listed firm

The deal covers the FLT3+Aurora kinases portfolio, including SAR-20293, a preclinical drug candidate for acute myeloid leukaemia and other blood-borne cancers

Sareum Holdings PLC -

Sareum Holdings PLC (LON:SAR) said it has inked a licensing deal with an unnamed Chinese specialty pharmaceutical company that will develop the UK firm's FLT3+Aurora kinases portfolio, including SAR-20293, a preclinical drug candidate for acute myeloid leukaemia and other blood-borne cancers.

The AIM-listed group will receive £50,000 upfront and a further £900,000 milestone payment related to oral bioavailability - the ability of the drug to reach the therapeutic area after being taken by mouth.

Sareum’s new partner is described as a vertically integrated group listed on the main market of the Shanghai Stock Exchange. It has been granted an exclusive worldwide licence to develop, manufacture and commercialise the Sareum discoveries.

“We believe the Licensee has the resources and expertise to further advance these molecules through the clinic to commercialisation in China,” Sareum chief executive, Dr Tim Mitchell said in a statement.

He added that the focus was now wholly on the firm’s pre-clinical TYK2/JAK1 inhibitors, small molecule discoveries for cancer and autoimmune diseases. Preparatory work is being made to advance candidates towards human trials.

In the meantime, the “programmes continue to attract interest from international pharmaceutical companies”, the firm said in a separate announcement covering its interim results.

In this update, Sareum said Sierra Oncology, its licensing partner for a potential cancer treatment called SRA737, is still seeking “non-dilutive strategic options” to take the drug to the next stage of development.

Dosing of patients in a phase I/II study using SRA737 as a single therapy was completed last October, while a separate, early-stage analysis of the drug in harness with a chemotherapy is expected to “complete shortly”.

In the six months ended December 31, Sareum posted a loss of £610,000, down from £760,000 a year earlier. As of that end date it had £1mln in the bank.

Quick facts: Sareum Holdings PLC

Price: 0.92 GBX

Market: AIM
Market Cap: £29.95 m

Add related topics to MyProactive

Create your account: sign up and get ahead on news and events


The Company is a publisher. You understand and agree that no content published on the Site constitutes a recommendation that any particular security, portfolio of securities, transaction, or investment strategy is...

In exchange for publishing services rendered by the Company on behalf of Sareum Holdings PLC named herein, including the promotion by the Company of Sareum Holdings PLC in any Content on the Site, the Company...



Morning Report: FTSE 100 slides as US/China tensions escalate

Headlines from the Proactive UK newsroom. The FTSE 100 slumped as China shut a US consulate in Chengdu in retaliation to a similar measure in Houston. The blue chip index fell 110 to 6,101. UK retail sales bounced 13.9% month-on-month June, following on from May’s 12.9% increase. Sales...

2 weeks, 3 days ago

2 min read