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Collagen Solutions PLC: DEEP DIVE

Collagen Solutions receives Stateside boost

We take a closer look at Collagen Solutions, which received third-party validation of its business model in the form of outside investment from a blue-chip US agriculture company
picture of a knee
OVERVIEW: COS The Big Picture
Key product ChondroMimetic is a minimally-invasive, surgically-placed scaffold which helps repair knee cartilage
  • Growing tissues business
  • Potentially breakthrough knee cartilage advance
  • Recent outside investment provides third-part validation of the firm's model 

What the company does…

Collagen Solutions PLC (LON:COS) specialises in regenerative medicines and biomaterials. It uses collagen and other tissue – such as pericardium – to make everything from heart valves to bone grafts right through to wound dressings: it all depends on what the customer wants.

Collagen has another string to its bow in the form of a lead product called ChondroMimetic. This is a minimally-invasive, surgically-placed scaffold which helps repair knee cartilage.

Last February, results from an eight-year clinical extension study showed ChondroMimetic was able to regenerate cartilage to a structural quality almost identical to native cartilage. Work on a CE Mark, which would signify that the product has passed European safety, health and environmental protection requirements, began almost straight after those results came in.

Collagen had hoped to hear whether or not it had been successful by the end of March, but, with the process out of its hands, it admitted recently the timing of any award was “uncertain”. Currently, ChondroMimetic is not approved for sale in any market, but Collagen has been working hard behind the scenes so that it is ready for sale as soon as the CE Mark is awarded.

“While there is no news on the regulatory front, we are gearing up for ChondroMimetic,” said Jamal Rushdy on May 20.

Fundraiser provides third-party validation

On that same day, Collagen said it was to raise £6mln at a premium to its share price, with a multi-billion-dollar US agriculture company agreeing to pump in the majority of the cash. Rosen’s Diversified, the fifth largest beef processor in the US and valued by Forbes at over £2.4bn (US$3bn), invested £4.2mln into Collagen. A separate placing and open offer at the same price among existing investors was launched raise up to a further £1.8mln.

The Rosen’s investment followed a tissue collaboration with Scientific Life Solutions, which is part of the American combine. “The conversation expanded as we saw a tremendous opportunity to work together,” said CEO Rushdy.

Deploying the cash

Chief financial officer Hilary Spence said the funds would be invested as follows:

  • £3mln will be invested in product and customer development
  • £1mln will be spent on expanding manufacturing capabilities
  • £2mln go towards paying down debt and funding ongoing capital requirements


In a trading statement on May 9, the company said its revenues for the 12 months to the end of March were a better than expected £4.15mln, up 18%. It exited the period with higher-than-anticipated £1.7mln in the bank.

Growth catalysts

Core business

  • New agreements from healthy deal pipeline
  • Milestones from development agreements
  • Customer product launches
  • Tissue business acceleration


  • Limited user release
  • Additional distribution

Product Pipeline

  • Partnering product

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Collagen Solutions PLC Timeline

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