Proactive Investors - Run By Investors For Investors

Midatech Pharma gets key clinical trial underway for cancer product

The US phase IV study will assess Gelclair's use in patients undergoing stem cell transplant therapy
Midatech Pharma gets key clinical trial underway for cancer product
The world-renowned Dana-Farber Institute will be on of two sites for the study

Midatech Pharma Plc(LON:MTPH, NASDAQ:MTP) said patient enrolment has begun for a clinical trial that could expand the market for its cancer treatment.

Gelclair is already prescribed for an after effect of radiation and chemo therapies called oral mucositis, a painful and debilitating inflammation and ulceration of the surface of the mouth.

The US phase IV study will assess the product's use in patients undergoing stem cell transplant therapy.

Two Massachusetts sites

It is being conducted at two sites - Dana-Farber/Brigham and Women's Cancer Centre and Massachusetts General Hospital - with recruitment expected to be completed by the middle of next year.

The trial will be randomised and double blind, which means one group will receive the medication and the other a dummy treatment called a placebo. Only at the end of the trial is it revealed who received what.

The main objective is to confirm the efficacy and tolerability of Gelclair for the treatment oral mucositis in people receiving allogeneic stem cell transplants alongside high-dose chemotherapy.  

Debilitating side-effects

"Oral mucositis is a debilitating side-effect often suffered by patients undergoing stem cell transplantation therapy, resulting in significant morbidity, pain, and discomfort," said David Benharris, the president of Midatech's US arm.   

"The expert treatment centres at Dana Farber and MGH are renowned for their work in stem cell transplant therapy therapy, and in this regard are already enrolling appropriate patients for trial participation.

"The trial aims to establish how Gelclair can assist healthcare professionals and stem cell transplant therapy units to better manage patient care, as well as improve upon the health care economics, relative to the treatment of oral mucositis, which is commonly seen in this patient population."

 

View full MTPH profile View Profile

Midatech Pharma PLC Timeline

Related Articles

Oncoprex
October 17 2018
The biotech was founded by an investment group led by scientists and driven by a no-nonsense CEO whose stake is more than just business as usual
child
February 08 2019
“If successful, this platform [AP103] has potential in other genetic skin conditions and beyond”
A syringe
January 30 2019
Leronlimab shows promise as an antiviral agent with fewer side effects, lower toxicity and less frequent doses than daily HIV therapies now in use

© Proactive Investors 2019

Proactive Investors Limited, trading as “Proactiveinvestors United Kingdom”, is Authorised and regulated by the Financial Conduct Authority.
Registered in England with Company Registration number 05639690. Group VAT registration number 872070825 FCA Registration number 559082. You can contact us here.

Market Indices, Commodities and Regulatory News Headlines copyright © Morningstar. Data delayed 15 minutes unless otherwise indicated. Terms of use