UK shares finished lower as markets reeled from downgraded UK growth forecasts.
The think tank - the Organisation for Economic Co-operation and Development (OECD) - cut its forecast for UK growth this year to 1.7%, from 2.2% it said three months ago, on the basis the country remains in the EU.
Meanwhile, also sending waves today was a new poll on the referendum, by The Times/YouGov, which showed that 41% support Bremain while 41% are in favour of a Brexit.
FTSE100 finished over 38 points lower at 6,191, with plumbers merchant Wolseley (LON:WOS) the biggest laggard.
The FTSE AIM All share lost 0.23% at 737.770, while FTSE AIM 100 lost 0.44% to 3,471.
Brent crude nudged up 1.73% to US$50 a barrel, while gold was up to 0.20% to US$1,214.
Wolseley plc (LON:WOS) lost over 5% to 3,828p despite it reporting higher profits and revenue but said markets had weakened.
Gross margin was ahead of last year at 28.4% and trading profit of £230mln was 12.2% ahead of last year at constant currencies.
The group said weaker US industrial markets and lower commodity prices offset good volume increases in the country's commercial and housing markets, reducing its US growth by 2.3%.
The biggest London riser, up almost 52% to 52p, as the services specialist Pennant International Group PLC (LON:PEN) won two aeronautical engineering training contracts in the Middle East.
Strategic Minerals PLC (LON:SML) was up again - 14.29% to 0.40p. Yesterday, shares surged as it reported nickel bearing sulphides were hit at the Hanns Camp project in Australia.
The junior is currently drilling its first holes at the deposit in Western Australia.
Medical device group Tissue Regenix Group PLC (LON:TRX) advanced almost 2% to 21.16p after it appointed Professor Shervanthi Homer-Vanniasinkam as a non-executive director.
Meanwhile, shares in Slovenia-focused Ascent Resources sank over 30% to 0.59p as it raised £500,000 in a discounted placing to give it sufficient working capital until the end of third-quarter 2016.