RISERS
GenSpera (OTCMKTS:GNSZ) rose 5.2% to $0.233 after the clinical-stage biotech company said it expects its brain cancer patients' mid-stage trial's final data to be released in the fourth quarter of next year.
Juniper Pharmaceuticals (NASDAQ:JNP) rose 6.8% to $11.24 after the specialty pharmaceutical company announced details of its portfolio pipeline, focused on three new product candidates to treat women's health conditions, at its Investor Day Wednesday.
Aoxing Pharmaceutical (NYSEMKT:AXN) climbed 6.8% to $1.41 after the specialty pharmaceutical company reported revenue almost doubled in the third quarter.
FALLERS
J.C. Penney (NYSE:JCP) sank 17% to $7.32 even as the U.S. retailer reported better-than-expected quarterly sales and a smaller-than-expected loss.
Fossil (NASDAQ:FOSL) plummetted 32% to $34.43 after the watch and jewellery group posted a 45% decline in profit for the third quarter and clipped guidance for full year 2015.
Vericel (NASDAQ:VCEL) fell 3.7% to $1.92 after the developer of patient-specific expanded cellular therapies reported a wider-than-expected loss in the third quarter.
Cisco Systems (NASDAQ:CSCO) declined 6.1% to 26.15 after saying that weaker global economic growth and the strength of the U.S. dollar are hurting international sales of its equipment that manages Internet traffic, prompting it to dial back forecasts.