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The Markets
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Medical technology & services

US drug regulator approves the first new schizophrenia drug in 30 years

The US Food and Drug Administration (FDA) has approved Cobenfy, the first new drug for schizophrenia in over 30 years, developed by Bristol Myers Squibb.

Taken as a twice-daily pill, the treatment combines xanomeline and trospium chloride to manage common symptoms such as hallucinations and delusions.

Unlike traditional antipsychotics, which target dopamine, Cobenfy focuses on acetylcholine, a brain chemical linked to memory and learning, offering a fresh approach to treatment.

Clinical trials suggest it may reduce the side effects typically associated with antipsychotic medications, like weight gain and movement disorders.

In trials, only 6% of patients stopped using Cobenfy due to side effects, a significant improvement compared to older antipsychotics.

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