The US Senate has approved a bill calling for a ban on TikTok in the country unless Chinese owner ByteDance sells its stake within nine months.
President Joe Biden said he intends to sign the bill into law after the House of Representatives voted through the bill last month.
The bill voted by Senators, which was part of a larger package that includes military aid for Ukraine, Israel, Taiwan and others, gained broad bipartisan support with a vote of 79 for and 18 against.
Senator Marco Rubio said: "For years we've allowed the Chinese Communist party to control one of the most popular apps in America that was dangerously short-sighted."
Shou Zi Chew, TikTok's Singapore-based CEO, said: "The company will continue to do all it can including exercising its legal rights to protect the platform."
TikTok previously stated that the bill "would trample the free speech rights" of Americans and "devastate seven million businesses", claiming the platform contributes $24 billion to the US economy per year.
ByteDance and TikTok have consistently denied any misuse of American user data and maintained that the social media platform operates independently of the Chinese government.
The Senate bill offers the potential for a prolonged legal battle, with possible delays in implementation.