Frontier IP Group - Exscientia announces joint initiative re COVID-19
Portfolio news - Exscientia announces joint initiative to identify COVID-19 drugs with
Through the transatlantic alliance, Exscientia has gained access to Calibr's collection of 15,000 clinically-ready molecules, those which have already been shown to be safe for use in humans or have passed pre-clinical safety studies.
Exscientia will start by rapidly screening the entire collection to identify existing compounds that could be repurposed to tackle COVID-19. In the longer term, the Company plans to use its AI to design even more effective compounds.
Exscientia has been working with Diamond Light Source, the
"Other of our portfolio companies are directly involved in support efforts to combat COVID-19. These include
Exscientia statement in full:
Exscientia announces joint initiative to identify COVID-19 drugs with Diamond Light Source and
· Transatlantic partnership seeks to identify COVID-19 antiviral treatments
· Exscientia to screen nearly every known approved and investigational drug - 15,000 clinical molecules - against key COVID-19 drug targets to progress rapid treatments
Exscientia, the leading artificial intelligence (AI) driven drug discovery company, today announced a joint initiative with Diamond Light Source, the
Through this alliance, Exscientia has gained access to Calibr's world's leading collection of 15,000 clinically-ready molecules. This collection includes launched drugs, additional compounds that have already been shown to be safe in humans and promising compounds that have passed pre-clinical safety studies. The collection, which has been funded by the
Exscientia will first apply its advanced biosensor platforms to rapidly screen the complete collection against key viral drug targets of SARS-CoV-2, the virus responsible for COVID-19. Three prioritised targets include; the 3CL protease, the NSP12-NSP7-NSP8 RNA polymerase complex (both of which are vital components for viral replication) and the virus's SPIKE protein, which interacts with the human cell receptor ACE2 in order to gain entry to human cells.
Exscientia's mission is to make safer, more sophisticated drugs available to all - more quickly and efficiently than ever before using it AI drug discovery platform. At this critical time globally, the company believes that a dual strategy to first identify opportunities in the existing set of known drugs and then work on new optimised molecules is an optimal path to start to protect the human population from this invasive disease.
Exscientia statement ends
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NOTES FOR EDITORS
Exscientia is a global Artificial Intelligence (AI)-driven drug discovery company. By fusing the power of the original AI with the experience of seasoned drug hunters, Exscientia's innovative Centaur Chemist™ platform enables breakthrough productivity gains as well as new approaches to improve drug efficacy.
Novel compounds are automatically designed and prioritised for synthesis by its AI systems, which rapidly evolve compounds towards the desired candidate criteria for clinical development. For more information visit us on www.exscientia.ai or follow us on Twitter @exscientialtd.
ABOUT DIAMOND LIGHT SOURCE
Diamond Light Source is the
In addition to these, Diamond offer access to several integrated laboratories including the Electron Bio-imaging Centre (eBIC) and the Electron Physical Science Imaging Centre (ePSIC). Diamond serves as an agent of change, addressing 21st century challenges such as disease, clean energy, food security and more. Since operations started, more than 14,000 researchers from both academia and industry have used Diamond to conduct experiments, with the support of approximately 700 world-class staff. More than 9,000 scientific articles have been published by our users and scientists.
Funded by the
Calibr was founded on the principle that the creation of new medicines can be accelerated by pairing world-class biomedical research with state-of-the-art drug discovery and development capabilities. Leveraging the unique scientific framework of
The Group looks to build and grow a portfolio of equity stakes and licence income by taking an active involvement in spin-out companies, including support for fund raising and collaboration with relevant industry partners at an early stage of development.
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