Proactiveinvestors United Kingdom 4D Pharma https://www.proactiveinvestors.co.uk Proactiveinvestors United Kingdom 4D Pharma RSS feed en Wed, 17 Jul 2019 09:22:21 +0100 http://blogs.law.harvard.edu/tech/rss Genera CMS action@proactiveinvestors.com (Proactiveinvestors) action@proactiveinvestors.com (Proactiveinvestors) <![CDATA[RNS press release - Holding(s) in Company ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190708155152_14140605/ Mon, 08 Jul 2019 15:51:52 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190708155152_14140605/ <![CDATA[RNS press release - Clinical Update ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190708070006_14139213/ Mon, 08 Jul 2019 07:00:06 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190708070006_14139213/ <![CDATA[RNS press release - Change of Adviser ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190701070010_14130324/ Mon, 01 Jul 2019 07:00:10 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190701070010_14130324/ <![CDATA[RNS press release - Result of AGM ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190620103846_14118282/ Thu, 20 Jun 2019 10:38:46 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190620103846_14118282/ <![CDATA[RNS press release - 4D presents MRx0518 combination study at ASCO ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190603070011_14095209/ Mon, 03 Jun 2019 07:00:11 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190603070011_14095209/ <![CDATA[RNS press release - Director/PDMR Shareholding ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190530070008_14091626/ Thu, 30 May 2019 07:00:08 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190530070008_14091626/ <![CDATA[RNS press release - Annual Report and Notice of AGM ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190528145035_14089537/ Tue, 28 May 2019 14:50:35 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190528145035_14089537/ <![CDATA[RNS press release - Director/PDMR Shareholding ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190523070009_14084402/ Thu, 23 May 2019 07:00:09 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190523070009_14084402/ <![CDATA[RNS press release - Director/PDMR Shareholding ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190522070006_14082715/ Wed, 22 May 2019 07:00:06 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190522070006_14082715/ <![CDATA[News - 4D Pharma shares drop as it falls to huge loss, warns it will need to raise money later this year ]]> https://www.proactiveinvestors.co.uk/companies/news/220681/4d-pharma-shares-drop-as-it-falls-to-huge-loss-warns-it-will-need-to-raise-money-later-this-year-220681.html Shares in 4D Pharma PLC (LON:DDDD) dropped on Tuesday as the drug developer warned it will have to tap the market for some more money within the next few months.

The AIM-listed company fell to a £24.3mln loss in 2018, after a loss of £19.4mln in 2017, as it moves its portfolio of cancer, irritable bowel syndrome and respiratory drugs through the clinic.

READ: 4D Pharma unaware of any reason for recent share price fall

That left it with £26.2mln of cash in the bank, almost half the amount it ended 2017 with at £50.0mln.

Bosses reckon that is enough to take 4D into the fourth quarter of this year, after which it will have to raise more money from somewhere.

“The directors are continuing to explore sources of finance available to the group and have a reasonable expectation that they will be able to secure sufficient cash inflows into the group to continue its activities for not less than twelve months from the date of approval of these accounts,” the group said.

4D Pharma shares fell 7.7% on Tuesday morning to 97.9p.

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Tue, 21 May 2019 10:00:00 +0100 https://www.proactiveinvestors.co.uk/companies/news/220681/4d-pharma-shares-drop-as-it-falls-to-huge-loss-warns-it-will-need-to-raise-money-later-this-year-220681.html
<![CDATA[RNS press release - Final Results ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190521070013_14080943/ Tue, 21 May 2019 07:00:13 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190521070013_14080943/ <![CDATA[RNS press release - 4D Presents Phase Ib Clinical Data on Thetanix® ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190516070006_14075870/ Thu, 16 May 2019 07:00:06 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190516070006_14075870/ <![CDATA[RNS press release - Participation in Conferences ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190513080001_14071130/ Mon, 13 May 2019 08:00:01 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190513080001_14071130/ <![CDATA[RNS press release - Clinical Update - MRx0518 oncology programmes ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190429070020_14054602/ Mon, 29 Apr 2019 07:00:20 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190429070020_14054602/ <![CDATA[RNS press release - Director/PDMR Shareholding ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190314070020_14001563/ Thu, 14 Mar 2019 07:00:20 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190314070020_14001563/ <![CDATA[RNS press release - Director/PDMR Shareholding ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190313090801_14000449/ Wed, 13 Mar 2019 09:08:01 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190313090801_14000449/ <![CDATA[RNS press release - Participation in Microbiome Conference ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190308070005_13994858/ Fri, 08 Mar 2019 07:00:05 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190308070005_13994858/ <![CDATA[RNS press release - Publication of data in connection with MRx0518 ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190129070009_13949565/ Tue, 29 Jan 2019 07:00:09 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190129070009_13949565/ <![CDATA[RNS press release - Appointment of independent Non-Executive Directors ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190108070005_13926645/ Tue, 08 Jan 2019 07:00:05 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190108070005_13926645/ <![CDATA[RNS press release - Collaboration with MD Anderson Cancer Center ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190107070006_13925041/ Mon, 07 Jan 2019 07:00:06 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20190107070006_13925041/ <![CDATA[RNS press release - Director/PDMR Shareholding ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181221070003_13912391/ Fri, 21 Dec 2018 07:00:03 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181221070003_13912391/ <![CDATA[RNS press release - Director/PDMR Shareholding ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181219070004_13908850/ Wed, 19 Dec 2018 07:00:04 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181219070004_13908850/ <![CDATA[RNS press release - PDMR Dealings ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181213070006_13901885/ Thu, 13 Dec 2018 07:00:06 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181213070006_13901885/ <![CDATA[RNS press release - Second Price Monitoring Extn ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181212164050_13901625/ Wed, 12 Dec 2018 16:40:50 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181212164050_13901625/ <![CDATA[RNS press release - Price Monitoring Extension ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181212163551_13901611/ Wed, 12 Dec 2018 16:35:51 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181212163551_13901611/ <![CDATA[News - 4D Pharma says it is unaware of any reasons for recent share price fall ]]> https://www.proactiveinvestors.co.uk/companies/news/211056/4d-pharma-says-it-is-unaware-of-any-reasons-for-recent-share-price-fall-211056.html 4D Pharma PLC (LON:DDDD) on Wednesday said it was not aware of any reason for the recent fall in its share price.

The pharmaceutical company also confirmed that all clinical study timelines continue to progress as expected.

READ: 4D Pharma bullish on progress of microbiome-based cancer research

“4D Pharma notes the recent fall in its share price and confirms that it is not aware of any company related matter which could be responsible for this price movement. The board also confirms that all clinical study timelines continue to progress as expected,” the company said in a statement.

Shares in 4D Pharma closed down 30% on Tuesday but were 10% up at 98p in late morning trade on Wednesday.

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Wed, 12 Dec 2018 11:27:00 +0000 https://www.proactiveinvestors.co.uk/companies/news/211056/4d-pharma-says-it-is-unaware-of-any-reasons-for-recent-share-price-fall-211056.html
<![CDATA[RNS press release - Trading Statement ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181212070003_13900134/ Wed, 12 Dec 2018 07:00:03 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181212070003_13900134/ <![CDATA[RNS press release - Clinical Update - Blautix Phase II study ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181108070004_13859249/ Thu, 08 Nov 2018 07:00:04 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20181108070004_13859249/ <![CDATA[RNS press release - Interim results ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180928070005_13807972/ Fri, 28 Sep 2018 07:00:05 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180928070005_13807972/ <![CDATA[RNS press release - Clinical update and publication of studies ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180924070004_13800988/ Mon, 24 Sep 2018 07:00:04 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180924070004_13800988/ <![CDATA[RNS press release - 4D asthma publication ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180814070014_13753910/ Tue, 14 Aug 2018 07:00:14 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180814070014_13753910/ <![CDATA[RNS press release - Publication - microbiota as HDAC inhibitors ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180730070009_13735212/ Mon, 30 Jul 2018 07:00:09 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180730070009_13735212/ <![CDATA[RNS press release - 4D Presents at IHMC 2018 ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180627070005_13694868/ Wed, 27 Jun 2018 07:00:05 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180627070005_13694868/ <![CDATA[RNS press release - Second Price Monitoring Extn ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180625164051_13692799/ Mon, 25 Jun 2018 16:40:51 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180625164051_13692799/ <![CDATA[RNS press release - Price Monitoring Extension ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180625163531_13692792/ Mon, 25 Jun 2018 16:35:31 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180625163531_13692792/ <![CDATA[RNS press release - MHRA and HPRA clear Blautix Phase II study ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180613070009_13677236/ Wed, 13 Jun 2018 07:00:09 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180613070009_13677236/ <![CDATA[RNS press release - Holding(s) in Company ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180612165156_13676937/ Tue, 12 Jun 2018 16:51:56 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180612165156_13676937/ <![CDATA[RNS press release - Clinical Collaboration Agreement ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180607070005_13670079/ Thu, 07 Jun 2018 07:00:05 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180607070005_13670079/ <![CDATA[RNS press release - 4D Presents Phase Ib Clinical Data on Blautix ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180604070007_13664778/ Mon, 04 Jun 2018 07:00:07 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180604070007_13664778/ <![CDATA[RNS press release - Result of AGM ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180521120858_13648881/ Mon, 21 May 2018 12:08:58 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180521120858_13648881/ <![CDATA[RNS press release - MRx0518 - Monotherapy trial approved ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180521070008_13647853/ Mon, 21 May 2018 07:00:08 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180521070008_13647853/ <![CDATA[RNS press release - Clinical Update - Blautix IND ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180508070008_13631754/ Tue, 08 May 2018 07:00:08 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180508070008_13631754/ <![CDATA[RNS press release - Annual Report and Notice of AGM ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180426070003_13618987/ Thu, 26 Apr 2018 07:00:03 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180426070003_13618987/ <![CDATA[RNS press release - Final Results ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180423070005_13613645/ Mon, 23 Apr 2018 07:00:05 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180423070005_13613645/ <![CDATA[News - 4D Pharma bullish on progress of microbiome-based cancer research ]]> https://www.proactiveinvestors.co.uk/companies/news/193541/4d-pharma-bullish-on-progress-of-microbiome-based-cancer-research-193541.html 4D Pharma PLC (LON:DDDD) will present data today outlining how its microbiome-based cancer treatment might activate the body’s response to the disease.

The company’s lead oncology candidate is MRx0518, a strain of live bacteria extracted from human faecal samples that in pre-clinical models has shown it can stimulate the immune system.

Duncan Peyton, chief executive, will highlight aspects of the mode of action of MRx0518 at the Microbiome R&D and Business Collaboration Forum in Rotterdam. 

Specific component

4D has identified a specific component of the bacteria, flaA, that plays a key role in the activity of MRx0518 and the body's response to cancer. 

Peyton said: "This is a key step in the development of a true microbiome-derived pharmaceutical product for the treatment of cancer. 

"Understanding the mode of action of MRx0518, through the identification of a specific gene product and its interaction with a high profile human oncology target, gives greater insight into its potential applications and benefits to cancer patients.”

Plans are at an advanced stage to open clinical studies for MRx0518 in the UK and the US in the near future.

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Wed, 21 Mar 2018 09:43:00 +0000 https://www.proactiveinvestors.co.uk/companies/news/193541/4d-pharma-bullish-on-progress-of-microbiome-based-cancer-research-193541.html
<![CDATA[RNS press release - Oncology candidate update ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180321070004_13574694/ Wed, 21 Mar 2018 07:00:04 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180321070004_13574694/ <![CDATA[RNS press release - Appointment of Joint Broker ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180220070005_13538701/ Tue, 20 Feb 2018 07:00:05 +0000 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20180220070005_13538701/ <![CDATA[RNS press release - Interim results ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20170928070004_13378001/ Thu, 28 Sep 2017 07:00:04 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20170928070004_13378001/ <![CDATA[RNS press release - Holding(s) in Company ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20170905125425_13352387/ Tue, 05 Sep 2017 12:54:25 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20170905125425_13352387/ <![CDATA[RNS press release - Issue of Equity ]]> https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20170824070004_13340106/ Thu, 24 Aug 2017 07:00:04 +0100 https://www.proactiveinvestors.co.uk/companies/rns/14428/LSE20170824070004_13340106/