Historically the Company was focused on the skincare and pharmaceutical businesses. In March 2010, after an extensive review by the Board of Directors of the Company and outside advisors, the Board elected to change the overall direction of the Company from these sectors to the natural resources sector. The Board realized that the business prospects of the existing portfolio of assets were not capable of generating sufficient revenue, and the Company had insufficient cash on hand to reach significant revenue generation from any of the product lines in the Company’s portfolio. The Company elected to pursue opportunities in the resources sector as this sector has been experiencing significant growth and investor interest in the past few years and the Board believes the sector has continued growth prospects and significant opportunities exist within the sector.

Here are some reasons to invest in Senetek Plc.

• Experienced Mining Team in place to identify and evaluate opportunity.
• Strong Supply/Demand Fundamentals for Metals led by Emerging Markets demand will continue for foreseeable future.
• Goal is to both produce from highly profitable operations as well as build shareholder value through in-ground resource expansion.
• Gray Eagle Mine represents first production opportunity – 2 stage copper / gold production cycle – existing updatable Feasibility Study has been completed.
• Iron Creek Mine represents second production opportunity – potentially 2nd largest Cobalt resource in USA.

Iron Creek

Copper Cobalt Opportunity

The Iron Creek is located in Lemhi County, Idaho near the Town of Salmon. The area is host to the largest known cobalt resource in CONUS owned by Formation Metals. The Iron Creek has been identified as the second largest cobalt resource in CONUS. Formation’s project is fully permitted and has recently received industrial development bonding support from Lemhi County to support construction of the project. Formation’s project is about 12 miles south of Iron Creek.

Highlights

• Copper-cobalt reserves on the order of 10 million tons of 2% copper equivalent with intercepts up to 25 ft grading 5.54% Cu and 0.19% Co in the No-Name zone
• Three additional copper-cobalt zones that have had only minor examination
• Gold target with a 1000 foot by 400 foot soil anomaly and rock chip samples up to 3.85 opt gold n High Grade underground cobalt deposit of around 1 million tons of 0.61% Co and 0.3% Cu (4.1% Cu equivalent)
• Similar mines within the same belt of rocks with past copper- cobalt production or known well-defined reserves
• 100% land ownership with no royalties, part of which is patented mining claims

Gray Eagle Mine

History

Found in 1890’s and had small historic production of copper and gold. Major exploration during WWI resulted in large tonnage of copper being outlined. Idle until WWII when mined by Newmont Mining.This was an underground operation and produced 462,000 tons of ore at 3.17% Cu and 0.027 opt Au. Shut down at the end of the war. SiskonCorp. acquired in mid-1950’s and leased to several explorers who outlined an open-pit resource. Noranda explored in late 70’sand put in to production in early 80’s and produced gold from a leached breccia amounting to 120,000 ounces. Noranda ceased operations in 1987. Siskonre evaluated the remaining copper resource and did a drilling program in 1989 to outline the current resource blocks. Senetek has acquired the project from a mining entrepreneur who acquired.

Geology

This is a Volcanogenic Massive Sulfide deposit or “VMS” deposit and is stratiform in the Galice formation. These types of deposits are common regionally and were formed originally on the seabed. Mineralization includes chalcopyrite and gold-bearing pyrite as well as minor amounts of sphalerite, covellite, and chalcocite. The most important ore host for our purposes are two massive pyrite-chalcopyrite zones which contain the known ore resource and known as the North and South Block. The structural geology of the ore body is well understood aiding continued definition drilling and resource expansion potential.

Project Parameters

Based on past work of Siskon Corporation as well as Feasibility Study of Pincock, Allen and Holt completed in May, 1990. Metal Prices used were $400 gold and $1.00 per pound copper. The Pincock Study projected an ore body of 1,130,000 tons would be mined at a cutoff grade of 1.0%. The average grade of ore mined was projected to be 2.59% Cu and 0.021 opt Au with 90% Cu recovery and 25% Au recovery using a flotation milling process. Capex in 1990 dollars for a 1,000 ton per day operation was approximately $10 million. Project was to be a small open pit with a strip ratio of 3.3:1. At prevailing historic base metal prices the project would make nearly $4 million over the five year project life. Importantly, the Pincock Study noted the project would make an additional $3.1 million over its mine life for every $0.10 rise in the copper price.

John Ryan- Chairman and CEO

• Entrepreneur primarily in the Resource Sector.
• Founder of Cadence Resources, High Plains Uranium, Western Goldfields, Metalline Mining Company, U.S. Silver and others.
• Responsible for successful acquisition of Aurora Energy by Cadence Resources growing Cadence from $5MM market cap in January, 2001 to $200MM market cap in 2004.
• Integral to successful start-up of High Plains Uranium growing company  from concept in July, 2004 to take out by NYSE listed company in eighteen months at over $100MM valuation.
• Integral to successful acquisition of Coeur Silver Valley assets into U.S. Silver and growing company to $200MM market cap in less than one year.
• B.S. from University of Idaho in Mining Engineering
• Juris Doctor from Boston College Law School.

Howard Crosby-President and CFO

• Entrepreneur primarily in the Resource Sector.
• Founder of Cadence Resources, High Plains Uranium, Western Goldfields, Metalline Mining Company, U.S. Silver and others.
• Responsible for successful acquisition of Aurora Energy by Cadence Resources growing Cadence from $5MM market cap in January, 2001 to $200MM market cap in 2004.
• Integral to successful start-up of High Plains Uranium growing company from concept in July, 2004 to take out by NYSE listed company in eighteen months at over $100MM valuation.
• Integral to successful acquisition of Coeur Silver Valley assets into U.S. Silver and growing company to $200MM market cap in less than one year.
• B.S. from University of Idaho
• Twenty-five  years of finance and resource industry experience

Wes Holland - Director/Bio-Med Consultant

Tony Williams - Vice Chairman and Director

Kerry Dukes - Director

Bobby Cooper - Director

John May - Director

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