YM Biosciences
YM BioSciences is engaged in the licensing and commercialization of drug products and technologies from original research.
The Company is advancing two late-stage products: nimotuzumab, a humanized monoclonal antibody that targets the epidermal growth factor receptor (EGFR) and is approved in several countries for treatment of various types of head and neck cancer, and AeroLEF, an inhaled-delivery composition of free and liposome-encapsulated fentanyl in development for the treatment of moderate to severe pain, including cancer pain.
Its products in clinical development target solid tumors, including colorectal, prostate, head and neck, breast, pancreatic, esophageal, specific types of brain tumors and acute pain, including cancer pain.
YM Biosciences’ Nimotuzamab selected for Phase III trial by Singapore
YM BioSciences Inc said the National Cancer Centre of Singapore (NCCS) has selected nimotuzumab, its epidermal growth factor receptor -targeting antibody, for evaluation in a multinational Phase III trial of more than 700 patients with cancers of the head and neck.
The NCCS stated that it selected nimotuzumab because of its reported preferential safety profile compared with other EGFR-targeting cancer drugs, the oncology group said. The trial is sponsored by the NCCS in collaboration with Innogene Kalbiotech Pte Ltd, YM's licensee for nimotuzumab for the region.
The NCCS is the lead cancer centre coordinating this clinical trial, which will involve approximately 22 institutions from 12 countries worldwide.
The primary endpoint for this study is two-year and five-year disease-free survival; the secondary endpoint is two-year and five-year overall survival.







