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Scancell presents Moditope data at prestigious cancer conference

Chief scientific officer Lindy Durrant presented two posters at the International Cancer Immunotherapy conference in Germany on Friday
conference hall
Data showed that Modi-1 had an anti-tumour effect on pancreatic, lung, ovarian and melanoma cancer models

Cancer drug developer Scancell Holdings PLC (LON:SCLP) presented the latest data from its Moditope platform at the International Cancer Immunotherapy conference in Germany – one of the most prestigious meetings in the industry’s calendar.

Moditope stimulates the production of killer CD4+ T cells that induce anti-tumour activity without toxicity.

The AIM-quoted firm’s chief scientific officer Lindy Durrant presented two posters at the conference on Friday.

LOOK: Take a look at the two posters

The data showed that Modi-1 – the lead product from the platform – induced strong anti-tumour immunity in pancreatic, lung, ovarian and melanoma cancer models with up to 100% survival.

“Our poster in collaboration with ISA Pharmaceuticals showed that Modi-1 conjugated to synthetic TLR1/2 agonists generated an anti-tumour response at up to 100-fold lower doses than Modi-1 alone and that these conjugated peptides induced a memory response against tumour re-challenge,” said Durrant.

“These results suggest that Modi-1 conjugated directly to TLR agonists could be a powerful new approach to the treatment of cancer.”

Shares rose 0.9% to 14.12p.

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Scancell Holdings Plc Timeline

February 08 2018

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