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Thursday March 18, 12:26Healthcare & Biotech companies to present at "Ultimate Healthcare & Biotechnology Event 2010”

We have a cracking line-up for March 24, as we return to Healthcare & Biotech sector at our One2One Investor Forum. Seats are limited, to avoid disappointment, register now.

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Thursday March 18, 02:18Can Europe march towards economic prosperity with a common currency but without a common government?

An apparently disappointed Mr. Papandreou has stated that he may turn to the International Monetary Fund for an emergency loan should the EU fail to provide adequate financial support.

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Monday March 15, 09:01China's growth boosting commodity prices

The latest economic figures from China have put pressure on the dollar and boosted a number of high-yielding currencies, including the Australian dollar and the South African rand.

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Independent International Investment Research

Independent International Investment Research PLC is the UK’s leading source of truly impartial research and strategy on global equities and currencies for broker-dealers, investment banks and asset managers – worldwide
Friday, November 06, 2009
Wyeth pipeline requires significant investment from Pfizer - IIR

Pfizer revenues continue to depict lacklustre performances due to weak sales of its blockbuster drugs such as Lipitor and Viagra, amongst others. Pfizer’s R&D pipeline continues to appear weak, with 11 of its 25 drugs in Phase 3 comprising line extensions.

The Wyeth acquisition was completed in October 2009 and Pfizer will start reporting performance from 4Q 09. Wyeth’s pipeline is strong but requires significant R&D investment from Pfizer.

Moreover, revenues are expected to remain under pressure, exacerbated by Lipitor’s patent expiry (starting next year). 38.9% of Pfizer’s revenues face patent expiry over next couple of years. Consequently, Pfizer has an upheaval task to rein in the revenue deterioration by focusing on new launches and Wyeth drugs.

The company continues to focus on Sutent and Lyrica. Although the long term outlook for both these drugs is positive, with the expected launch of line extensions over the next couple of years; in the medium term these drugs are expected to grow at a modest pace. As the consolidation of Wyeth has begun and the company will report partial performance in 4Q 09, we expect a negative impact on consolidated margins over the medium term. Moreover, patent expiry of blockbuster drugs will have a lasting impact on operating performance.

Pfizer has gross margin of approximately 85%, compared to Wyeth’s 71%. We continue to expect Pfizer, with Wyeth’s consolidation and its low cost sourcing strategies to be able to achieve higher economies of scale, thereby bridging the gap between both companies’ gross margins over the next 2 years. Moreover, net margin will be hampered by high interest charges streaming from the increased debt following the Wyeth’s acquisition.

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Independent International Investment Research PLC supplies this research via Pronet Analytics.com Ltd. ('Pronet'). Pronet is Regulated and Authorized by the Financial Services Authority (FSA) and registered with the Securities Exchange Commission (SEC).

You are reminded that investment advice provided by Pronet is for your general information and use and is not intended to address your particular requirements. Any advice or recommendations contained in this report may not be suitable for you and are not intended to be relied upon by you in the making (or refraining from making) any specific investment or other decision. Such decisions should only be made on the basis of independent advice from an appropriately qualified adviser.

Pronet Analytics.com Ltd. and Independent Financial Markets Research Ltd. are subsidiaries of Independent International Investment Research PLC (the 'Group'). Research analysts working for the Group are subject to stringent confidentiality and security policies and are located in secure-access premises which may be in the proximity of professionals conducting similar work for other firms.

The Group is not nor has been nor will be engaged in investment banking and does not make markets in any of the securities covered in this report or have any investment banking relationship with the firm whose security is covered in this report. No employee or contractor of the Group is permitted to personally buy or sell stock in the company covered in this report, and neither the analysts responsible for the report nor any related household members are officers, directors, or advisory board members of any covered company. No one at a covered company is on the Board of Directors of the Group or any of its affiliates.

This report is not a solicitation to buy or sell any security and past performance is no guarantee of future results.


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